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Table 2 Differentially expressed genes in the two congenic intervals

From: The influence of the NOD Nss1/Idd5 loci on sialadenitis and gene expression in salivary glands of congenic mice

Gene ID Gene symbola Gene name Fold changeb
    B10.Q versus NB B10.Q versus NBI NB versus NBI
215627 Zbtb8 Zinc finger and BTB domain containing 8 3.7 4.4  
384059 Tlr12 Toll-like receptor 12 3.3   
381549 Zfp69 Zinc finger protein 69 3.2 3.3  
230779 Serinc2 Serine incorporator 2 3 2.2  
16818 Lck Lymphocyte protein tyrosine kinase 2.9 3  
12260 C1qb Complement component 1, q subcomponent, beta polypeptide 2.8 1.8  
23833 Cd52 CD52 antigen 2.5 2  
12259 C1qa Complement component 1, q subcomponent, alpha polypeptide 2.4 1.7  
20846 Stat1 Signal transducer and activator of transcription 1 2.2 1.8  
14268 Fn1 Fibronectin 1 2.2 1.7  
14612 Gja4 Gap junction membrane channel protein alpha 4   2.2  
18991 Pou3f1 POU domain, class 3, transcription factor 1   2.2  
11520 Adfp Adipose differentiation related protein 2.1 1.7  
107581 Col16a1 Procollagen, type XVI, alpha 1 2.1 1.6  
269582 Clspn Claspin homolog (Xenopus laevis)   2.1  
16792 Laptm5 Lysosomal-associated protein transmembrane 5 1.9 1.8  
12579 Cdkn2b Cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 1.9 1.6  
20970 Sdc3 Syndecan 3 1.9 1.6  
20720 Serpine2 Serine (or cysteine) peptidase inhibitor, clade E, member 2 1.8   
14700 Gng10 Guanine nucleotide binding protein (G protein), gamma 10   1.8  
230657 Tmem69 Transmembrane protein 69 1.7 1.5  
16008 Igfbp2 Insulin-like growth factor binding protein 2 1.7   
73723 Sh3bgrl3 SH3 domain binding glutamic acid-rich protein-like 3 1.7   
93691 Klf7 Kruppel-like factor 7 (ubiquitous) 1.6   -1.6
66290 Atp6v1g1 ATPase, H+ transporting, V1 subunit G isoform 1 1.6   
27981 D4Wsu53e DNA segment, Chr 4, Wayne State University 53, expressed 1.6   
17965 Nbl1 Neuroblastoma, suppression of tumorigenicity 1 1.6   
67103 Ltb4dh Leukotriene B4 12-hydroxydehydrogenase    1.6
230379 Asah3l N-acylsphingosine amidohydrolase 3-like    1.6
19231 Ptma Prothymosin alpha 1.5   
68777 Tmem53 Transmembrane protein 53   1.5  
320438 Alg6 Asparagine-linked glycosylation 6 homolog (yeast, alpha-1,3,-glucosyltransferase)   1.5  
101739 Psip1 PC4 and SFRS1 interacting protein 1    1.5
230861 Eif4g3 Eukaryotic translation initiation factor 4 gamma, 3 -1.5 -1.7  
74648 S100pbp S100P binding protein -1.5   
101739 Psip1 PC4 and SFRS1 interacting protein 1 -1.5   
18710 Pik3r3 Phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55) -1.5   
67694 Ift74 Intraflagellar transport 74 homolog (Chlamydomonas) -1.5   
76850 Eif2c4 Eukaryotic translation initiation factor 2C, 4   -1.5  
19359 Rad23b RAD23b homolog (S. cerevisiae)   -1.5 -1.8
319146 Ifnz Interferon zeta    -1.5
100206 Adprhl2 ADP-ribosylhydrolase like 2   -1.6 -1.7
230815 Man1c1 Mannosidase, alpha, class 1C, member 1   -1.6  
67299 Dock7 Dedicator of cytokinesis 7 -1.6 -1.8  
21885 Tle1 Transducin-like enhancer of split 1, homolog of Drosophila E(spl) -1.7   
66902 Mtap Methylthioadenosine phosphorylase   -1.8  
11363 Acadl Acetyl-coenzyme A dehydrogenase, long-chain    -1.8
71872 Aox4 Aldehyde oxidase 4 -1.9   
236511 Eif2c1 Eukaryotic translation initiation factor 2C, 1 -2.1 -1.8  
58864 Tssk3 Testis-specific serine kinase 3 -3.2   
13370 Dio1 Deiodinase, iodothyronine, type I -3.4 -2.3  
66264 Ccdc28b Coiled coil domain containing 28B -4.2 -4.3  
66260 Tmem54 Transmembrane protein 54 -5 -8  
74754 Dhcr24 24-Dehydrocholesterol reductase -12.7 -13.8  
  1. aGenes on chromosome 1 (Idd5) lie within the markers D1Mit48 and D1Mit235, and genes on chromosome 4 (Nss1) lie within the markers D4Mit48 and D4Mit111. Genes with underlined gene symbols are in the Idd5 fragment. Unknown expressed sequence tags and genes with fold change < ± 1.5 were removed. bThe fold change is the relative intensities for each gene from the microarray gene lists B10.Q versus B10.Q.Nss1, B10.Q versus B10.Q.Nss1/Idd5 and B10.Q.Nss1 versus B10.Q.Nss1/Idd5, respectively. Genes with positive fold change were upregulated in the congenic mice, and in B10.Q.Nss1/Idd5 when compared with B10.Q.Nss1. NB, B10.Q.Nss1; NBI, B10.Q.Nss1/Idd5-he and B10.Q.Nss1/Idd5-ho.