Figure 7From: Src kinase inhibition promotes the chondrocyte phenotypePP2 promotes cell rounding and cortical actin formation. Primary mouse chondrocytes were incubated for 24 hours with (a) dimethyl sulphoxide or (b) the Src inhibitor PP2 (10 μmol/l), and cells were stained with rhodamine-phalloidin (red) for polymerized actin and with DAPI for nuclei (blue). PP2 induced cell rounding, loss of stress fibre, and cortical organization of actin (scale bar: 2 μm).Back to article page