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Table 1 Baseline characteristics of study population (n = 137)

From: Cartilage markers and their association with cartilage loss on magnetic resonance imaging in knee osteoarthritis: the Boston Osteoarthritis Knee Study

  Whole sample No cartilage loss in any plate (at follow-up) (n = 66) Cartilage loss in any plate (at follow-up) (n = 71)
Age in years, mean ± SD 67 ± 9 66 ± 9 67 ± 10
Males, number (percentage) 74 (54%) 38 (58%) 36 (51%)
Body mass index, mean (SD) 31.43 (5.48) 31.03 (6.08) 31.75 (4.87)
Percentage with K&L grade of ≥ 2 73% 67% 80%
Number of plates with cartilage loss, mean (SD) 0.99 (1.24) 0 (0) 1.92 (1.09)
Mean interval in years between baseline and follow-up scan 2.67 2.68 2.66
Levels of biomarkers, mean (SD)    
   COMP 12.5 (2.9) 11.9 (2.9) 13.0 (2.9)
   846 epitope 269.3 (154.2) 273.4 (154.6) 265.4 (154.8)
   CPII 1,660.9 (598.5) 1,635.9 (623.9) 1,684.1 (577.3)
   C1,2C 0.06 (0.03) 0.06 (0.03) 0.06 (0.03)
   Col2CTX/Cr ratio 51.77 (63.53) 45.82 (31.81) 57.62 (83.70)
   C2C 53.2 (22.9) 57.0 (28.6) 49.7 (15.5)
  1. C2C, collagenase cleavage of triple-helical type II collagen; Col2CTx, crosslinked peptides from the C-telopeptide domain of type II collagen; COMP, cartilage oligomeric matrix protein; CPII, C-propeptide of type II collagen; K&L, Kellgren & Lawrence; SD, standard deviation.