Table 1 Baseline characteristics of study population (n = 137)
| Â | Whole sample | No cartilage loss in any plate (at follow-up) (n = 66) | Cartilage loss in any plate (at follow-up) (n = 71) |
|---|---|---|---|
Age in years, mean ± SD | 67 ± 9 | 66 ± 9 | 67 ± 10 |
Males, number (percentage) | 74 (54%) | 38 (58%) | 36 (51%) |
Body mass index, mean (SD) | 31.43 (5.48) | 31.03 (6.08) | 31.75 (4.87) |
Percentage with K&L grade of ≥ 2 | 73% | 67% | 80% |
Number of plates with cartilage loss, mean (SD) | 0.99 (1.24) | 0 (0) | 1.92 (1.09) |
Mean interval in years between baseline and follow-up scan | 2.67 | 2.68 | 2.66 |
Levels of biomarkers, mean (SD) | Â | Â | Â |
   COMP | 12.5 (2.9) | 11.9 (2.9) | 13.0 (2.9) |
   846 epitope | 269.3 (154.2) | 273.4 (154.6) | 265.4 (154.8) |
   CPII | 1,660.9 (598.5) | 1,635.9 (623.9) | 1,684.1 (577.3) |
   C1,2C | 0.06 (0.03) | 0.06 (0.03) | 0.06 (0.03) |
   Col2CTX/Cr ratio | 51.77 (63.53) | 45.82 (31.81) | 57.62 (83.70) |
   C2C | 53.2 (22.9) | 57.0 (28.6) | 49.7 (15.5) |