Table 2 Genotype distribution of the six catechol-O-methyltransferase single-nucleotide polymorphisms in patients and healthy controls from Mexico and Spain
From: Catechol-O-methyltransferase gene haplotypes in Mexican and Spanish patients with fibromyalgia
Spanish | Mexican | |||||
|---|---|---|---|---|---|---|
Genotype | Patients | Controls | P value | Patients | Controls | P value |
n (%) | n (%) | n (%) | n (%) | |||
rs6269 | ||||||
AA | 21 (27) | 14 (18) | 0.015a | 30 (53) | 17 (52) | NS |
AG | 42 (54) | 34 (42) | 21 (37) | 13 (39) | ||
GG | 15 (19) | 32 (40) | 6 (10) | 3 (9) | ||
rs4633 | ||||||
CC | 28 (36) | 19 (24) | NSa | 21 (37) | 17 (52) | NS |
CT | 36 (46) | 37 (46) | 28 (49) | 13 (39) | ||
TT | 14 (18) | 24 (30) | 8 (14) | 3 (9) | ||
rs4818 | ||||||
CC | 19 (24) | 13 (16) | 0.001 | 30 (53) | 15 (46) | NS |
CG | 47 (60) | 33 (41) | 21 (36) | 12 (36) | ||
GG | 12 (16) | 34 (43) | 6 (11) | 6 (18) | ||
rs4680 | ||||||
AA | 9 (12) | 22 (27) | 0.023a | 2 (4) | 4 (12) | NS |
AG | 40 (51) | 39 (49) | 32 (56) | 14 (42) | ||
GG | 29 (37) | 19 (24) | 23 (40) | 15 (46) | ||
rs20907 | ||||||
AA | 31 (40) | 23 (29) | NSa | 26 (46) | 15 (45.5) | NS |
AG | 34 (43) | 40 (50) | 24 (42) | 15 (45.5) | ||
GG | 13 (17) | 17 (21) | 7 (12) | 3 (9) | ||
rs16559 | ||||||
AA | 36 (46) | 33 (41) | NSa | 12 (21) | 10 (30) | NSa |
AG | 30 (39) | 35 (44) | 32 (56) | 15 (46) | ||
GG | 12 (15) | 12 (15) | 13 (23) | 8 (24) | ||