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Figure 2 | Arthritis Research & Therapy

Figure 2

From: Differential expression of the FAK family kinases in rheumatoid arthritis and osteoarthritis synovial tissues

Figure 2

Rheumatoid arthritis synovial tissue (RA ST) had higher pPyk2 immunopositive cells compared to osteoarthritis (OA) ST. (a) RA (×200), compared to (b) OA (×200) and (c) normal donor (ND) (×200). (d) is the quantification data obtained from figure a and b. Bars represent mean and SEM. RA ST fibroblasts (e and f) or peripheral blood differentiated MΦs (g and h) were stimulated with TNF-α (10 ng/ml) or IL1-β (10 ng/ml) from 0–120 min. Cell lysates were examined by western blot analysis for pPyk2 or Pyk2 expression. The results are representative of three experiments. Inflam, inflammatory score; Vasc, vascularity score; Lining, ST lining cell layer; Mac, subsynovial MΦs.

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