Mother ever diagnosed with SLE | Mother never diagnosed with SLE | |||
---|---|---|---|---|
Pregnancies conceived before mother's SLE diagnosis | Pregnancies conceived after mother's SLE diagnosis | All pregnancies conceived by mothers ever diagnosed with SLE | ||
Total number of pregnancies | 274 (100%) | 78 (100%) | 352 (100%) | 667 (100%) |
Mean (standard deviation) maternal age at conception | 25.0 (5.5) | 30.1 (5.6) | 25.6 (5.8) | 26.3 (6.1) |
Pregnancy type | ||||
Live birth | 224/274 (81.8%) | 33/78 (42.3%) | 257/352 (73.0%) | 553/667 (82.9) |
Foetal death | 47/274 (17.2%) | 43/78 (55.1%) | 90/352 (25.6%) | 109/667 (16.3%) |
First-trimester miscarriage (0–12 weeks)b | 28/274 (10.2%) | 34/78 (43.6%) | 62/352 (17.6%) | 90/667 (13.4%) |
Mid-trimester miscarriage (13–23 weeks)b | 3/259 (1.2%) | 4/49 (8.2%) | 7/315 (2.2%) | 9/605 (1.5%) |
Miscarriage missing gestation | 3/274 (1.1%) | 1/78 (1.3%) | 4/352 (1.1%) | 1/667 (0.1%) |
Stillbirth (≥ 24 weeks)c | 13/237 (5.5%) | 4/37 (10.8%) | 17/274 (6.2%) | 9/562 (1.6%) |
Ectopic pregnancy | 3/274 (1.1%) | 2/78 (2.6%) | 5/352 (1.4%) | 5/667 (0.7%) |
Reported gestation of live births (completed weeks) | ||||
All pregnancies ending in live birth | 224 (100%) | 33 (100%) | 257 (100%) | 553 (100%) |
< 24 weeks | 5 (2.2%) | 3 (9.1%) | 8 (3.1%) | 20 (3.6%) |
24–31 weeks | 2 (0.9%) | 3 (9.1%) | 5 (2.0%) | 2 (0.4%) |
32–36 weeks | 5 (2.2%) | 1 (3.0%) | 6 (2.3%) | 4 (0.7%) |
All preterm (< 37 weeks) | 12 (5.4%) | 7 (21.2%) | 19 (7.4%) | 26 (4.7%) |
37–42 weeks | 212 (94.6%) | 26 (78.8%) | 238 (92.6%) | 526 (95.1%) |
42–46 weeks | 0 (0%) | 0 (0%) | 0 | 1 (0.2%) |
Reported gestation of foetal deaths (completed weeks) | ||||
All pregnancies ending in foetal deathb | 47 (100%) | 43 (100%) | 90 (100%) | 109 (100%) |
< 8 weeks | 17 (36.2%) | 25 (58.1%) | 42 (46.7%) | 63 (57.8%) |
8–12 weeks | 11 (23.4%) | 9 (20.9%) | 20 (22.2%) | 28 (25.7%) |
13–15 weeks | 2 (4.3%) | 0 (0%) | 2 (2.2%) | 4 (3.7%) |
16–23 weeks | 1 (2.1%) | 4 (9.3%) | 5 (5.6%) | 5 (4.6%) |
24–36 weeks | 6 (12.7%) | 4 (9.3%) | 10 (11.1%) | 4 (3.7%) |
≥ 37 weeks | 7 (14.9%) | 0 (0%) | 7 (7.7%) | 3 (2.8%) |
Missing gestation category | 3 (6.4%) | 1 (2.3%) | 4 (4.4%) | 2 (1.8%) |