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Table 1 The KIR phenotype on NK cells stimulated with IL-2, Il-15 and IL-21.

From: The proinflammatory cytokines IL-2, IL-15 and IL-21 modulate the repertoire of mature human natural killer cell receptors

  Day 0 Day 7 + IL-2 Day 7 + IL-15 Day 7 + IL-2/IL-21 Day 7 + IL-15/IL-21
CD56dim      
   Negative 26.63 27.77 24.16 31.28 27.66
   158i 37.57 38.81 40.33 36.53 40.00
   158b1-b2-j 3.46 5.81 3.97 4.46 3.41
   158e1 4.16 1.45 1.83 1.46 2.30
   158a-h 3.97 2.71 3.22 3.23 3.27
   158b1-b2-j/158i 9.04 12.29 11.28 11.57 8.92
   158a-h/158i 5.60 3.77 5.37 3.76 4.71
   158e1/158i 2.24 2.24 3.41 2.39 3.29
   158a-h/158b1-b2-j 0.89 0.97 0.72 0.67 0.78
   158e1/158b1-b2-j 1.64 0.35 0.72 0.61 0.66
   158e1/158a-h 0.80 0.32 0.36 0.30 0.50
   158a-h/158b1-b2-j/158i 2.32 2.06 2.02 1.75 2.06
   158e1/158b1-b2-j/158i 0.68 0.63 1.31 0.96 1.30
   158e1/158a-h/158i 0.42 0.50 0.66 0.50 0.70
   158e1/158a-h/158b1-b2-j 0.41 0.10 0.22 0.21 0.14
   158e1/158a-h/158b1-b2-j/158i 0.17 0.18 0.41 0.32 0.30
CD56bright      
   Negative 62.86 65.69 56.57 71.55 75.24
   158i 17.86 17.89 20.87 15.75 13.20
   158b1-b2-j 1.67 6.11 8.34 5.45 5.48
   158e1 2.38 1.87 2.17 1.29 1.24
   158a-h 3.81 1.20 0.77 0.86 1.16
   158b1-b2-j/158i 4.76 3.44 8.01 3.56 2.54
   158a-h/158i 1.19 0.33 0.28 0.19 0.20
   158e1/158i 2.38 0.62 0.51 0.22 0.36
   158a-h/158b1-b2-j 0.71 1.00 0.23 0.15 0.12
   158e1/158b1-b2-j 0.00 0.89 1.22 0.65 0.00
   158e1/158a-h 0.00 0.13 0.10 0.00 0.16
   158a-h/158b1-b2-j/158i 2.38 0.56 0.21 0.11 0.06
   158e1/158b1-b2-j/158i 0.00 0.22 0.70 0.22 0.20
   158e1/158a-h/158i 0.00 0.04 0.02 0.00 0.04
   158e1/158a-h/158b1-b2-j 0.00 0.00 0.00 0.00 0.00
   158e1/158a-h/158b1-b2-j/158i 0.00 0.00 0.00 0.00 0.00
  1. Anti-CD158a recognize KIR2DL1 (CD158a) and KIR2DS1 (CD158h). Anti-CD158b recognize KIR2DL2 (CD158b1), KIR2DL3 (CD158b2) and KIR2DS2 (CD158j). Anti-NKB1 is specific for KIR3DL1 (CD158e1). Anti-KARp50.3 recognize KIR2DS4 (CD158i). KIR, killer cell immunoglobulin-like receptor.