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Table 1 The KIR phenotype on NK cells stimulated with IL-2, Il-15 and IL-21.

From: The proinflammatory cytokines IL-2, IL-15 and IL-21 modulate the repertoire of mature human natural killer cell receptors

 

Day 0

Day 7 + IL-2

Day 7 + IL-15

Day 7 + IL-2/IL-21

Day 7 + IL-15/IL-21

CD56dim

     

   Negative

26.63

27.77

24.16

31.28

27.66

   158i

37.57

38.81

40.33

36.53

40.00

   158b1-b2-j

3.46

5.81

3.97

4.46

3.41

   158e1

4.16

1.45

1.83

1.46

2.30

   158a-h

3.97

2.71

3.22

3.23

3.27

   158b1-b2-j/158i

9.04

12.29

11.28

11.57

8.92

   158a-h/158i

5.60

3.77

5.37

3.76

4.71

   158e1/158i

2.24

2.24

3.41

2.39

3.29

   158a-h/158b1-b2-j

0.89

0.97

0.72

0.67

0.78

   158e1/158b1-b2-j

1.64

0.35

0.72

0.61

0.66

   158e1/158a-h

0.80

0.32

0.36

0.30

0.50

   158a-h/158b1-b2-j/158i

2.32

2.06

2.02

1.75

2.06

   158e1/158b1-b2-j/158i

0.68

0.63

1.31

0.96

1.30

   158e1/158a-h/158i

0.42

0.50

0.66

0.50

0.70

   158e1/158a-h/158b1-b2-j

0.41

0.10

0.22

0.21

0.14

   158e1/158a-h/158b1-b2-j/158i

0.17

0.18

0.41

0.32

0.30

CD56bright

     

   Negative

62.86

65.69

56.57

71.55

75.24

   158i

17.86

17.89

20.87

15.75

13.20

   158b1-b2-j

1.67

6.11

8.34

5.45

5.48

   158e1

2.38

1.87

2.17

1.29

1.24

   158a-h

3.81

1.20

0.77

0.86

1.16

   158b1-b2-j/158i

4.76

3.44

8.01

3.56

2.54

   158a-h/158i

1.19

0.33

0.28

0.19

0.20

   158e1/158i

2.38

0.62

0.51

0.22

0.36

   158a-h/158b1-b2-j

0.71

1.00

0.23

0.15

0.12

   158e1/158b1-b2-j

0.00

0.89

1.22

0.65

0.00

   158e1/158a-h

0.00

0.13

0.10

0.00

0.16

   158a-h/158b1-b2-j/158i

2.38

0.56

0.21

0.11

0.06

   158e1/158b1-b2-j/158i

0.00

0.22

0.70

0.22

0.20

   158e1/158a-h/158i

0.00

0.04

0.02

0.00

0.04

   158e1/158a-h/158b1-b2-j

0.00

0.00

0.00

0.00

0.00

   158e1/158a-h/158b1-b2-j/158i

0.00

0.00

0.00

0.00

0.00

  1. Anti-CD158a recognize KIR2DL1 (CD158a) and KIR2DS1 (CD158h). Anti-CD158b recognize KIR2DL2 (CD158b1), KIR2DL3 (CD158b2) and KIR2DS2 (CD158j). Anti-NKB1 is specific for KIR3DL1 (CD158e1). Anti-KARp50.3 recognize KIR2DS4 (CD158i). KIR, killer cell immunoglobulin-like receptor.