| |
Day 0
|
Day 7 + IL-2
|
Day 7 + IL-15
|
Day 7 + IL-2/IL-21
|
Day 7 + IL-15/IL-21
|
|---|
|
CD56dim
| | | | | |
|
Negative
|
26.63
|
27.77
|
24.16
|
31.28
|
27.66
|
|
158i
|
37.57
|
38.81
|
40.33
|
36.53
|
40.00
|
|
158b1-b2-j
|
3.46
|
5.81
|
3.97
|
4.46
|
3.41
|
|
158e1
|
4.16
|
1.45
|
1.83
|
1.46
|
2.30
|
|
158a-h
|
3.97
|
2.71
|
3.22
|
3.23
|
3.27
|
|
158b1-b2-j/158i
|
9.04
|
12.29
|
11.28
|
11.57
|
8.92
|
|
158a-h/158i
|
5.60
|
3.77
|
5.37
|
3.76
|
4.71
|
|
158e1/158i
|
2.24
|
2.24
|
3.41
|
2.39
|
3.29
|
|
158a-h/158b1-b2-j
|
0.89
|
0.97
|
0.72
|
0.67
|
0.78
|
|
158e1/158b1-b2-j
|
1.64
|
0.35
|
0.72
|
0.61
|
0.66
|
|
158e1/158a-h
|
0.80
|
0.32
|
0.36
|
0.30
|
0.50
|
|
158a-h/158b1-b2-j/158i
|
2.32
|
2.06
|
2.02
|
1.75
|
2.06
|
|
158e1/158b1-b2-j/158i
|
0.68
|
0.63
|
1.31
|
0.96
|
1.30
|
|
158e1/158a-h/158i
|
0.42
|
0.50
|
0.66
|
0.50
|
0.70
|
|
158e1/158a-h/158b1-b2-j
|
0.41
|
0.10
|
0.22
|
0.21
|
0.14
|
|
158e1/158a-h/158b1-b2-j/158i
|
0.17
|
0.18
|
0.41
|
0.32
|
0.30
|
|
CD56bright
| | | | | |
|
Negative
|
62.86
|
65.69
|
56.57
|
71.55
|
75.24
|
|
158i
|
17.86
|
17.89
|
20.87
|
15.75
|
13.20
|
|
158b1-b2-j
|
1.67
|
6.11
|
8.34
|
5.45
|
5.48
|
|
158e1
|
2.38
|
1.87
|
2.17
|
1.29
|
1.24
|
|
158a-h
|
3.81
|
1.20
|
0.77
|
0.86
|
1.16
|
|
158b1-b2-j/158i
|
4.76
|
3.44
|
8.01
|
3.56
|
2.54
|
|
158a-h/158i
|
1.19
|
0.33
|
0.28
|
0.19
|
0.20
|
|
158e1/158i
|
2.38
|
0.62
|
0.51
|
0.22
|
0.36
|
|
158a-h/158b1-b2-j
|
0.71
|
1.00
|
0.23
|
0.15
|
0.12
|
|
158e1/158b1-b2-j
|
0.00
|
0.89
|
1.22
|
0.65
|
0.00
|
|
158e1/158a-h
|
0.00
|
0.13
|
0.10
|
0.00
|
0.16
|
|
158a-h/158b1-b2-j/158i
|
2.38
|
0.56
|
0.21
|
0.11
|
0.06
|
|
158e1/158b1-b2-j/158i
|
0.00
|
0.22
|
0.70
|
0.22
|
0.20
|
|
158e1/158a-h/158i
|
0.00
|
0.04
|
0.02
|
0.00
|
0.04
|
|
158e1/158a-h/158b1-b2-j
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
|
158e1/158a-h/158b1-b2-j/158i
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
- Anti-CD158a recognize KIR2DL1 (CD158a) and KIR2DS1 (CD158h). Anti-CD158b recognize KIR2DL2 (CD158b1), KIR2DL3 (CD158b2) and KIR2DS2 (CD158j). Anti-NKB1 is specific for KIR3DL1 (CD158e1). Anti-KARp50.3 recognize KIR2DS4 (CD158i). KIR, killer cell immunoglobulin-like receptor.
