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Figure 2 | Arthritis Research & Therapy

Figure 2

From: Activator protein 1 (Fos/Jun) functions in inflammatory bone and skin disease

Figure 2

Heterogeneous JunB expression within lesional psoriatic skin. Immune reactivity of a monoclonal antibody against JunB within a psoriatic lesion. (a) Distinct anti JunB reactivity of a parakeratotic lesion. JunB expression is observed throughout all epidermal layers (left side, arrow), whereas it is reduced on the right side of the lesion (see arrow). (b) A different area of the same lesion. A virtual absence of nuclear reactivity is seen in basal keratinocytes, whereas strong nuclear activity is detected in the upper suprabasal epidermal layers ((a) and (b) arrows).

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