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Table 3 Effect of PPAR-γ agonists on incidence of adjuvant arthritis

From: Anti-inflammatory effect of antidiabetic thiazolidinediones prevents bone resorption rather than cartilage changes in experimental polyarthritis

Group Experiment
  1 2 3
AIA 5/5 6/6 7/7
AIA + ROSI 3 5/6 - -
AIA + ROSI 10 5/5 7/7 8/8
AIA + PIO 3 6/6 - -
AIA + PIO 10 6/6 - -
AIA + PIO 30 6/6 6/7 8/8
  1. PPAR, peroxisome proliferator-activated receptor; AIA, adjuvant-induced arthritis; ROSI, rosiglitazone 3 or 10 mg/kg/day; PIO, pioglitazone 3 or 10 or 30 mg/kg/day. Results are disease incidences at day 21.