Cost-utility of an 8-month aquatic training for women with fibromyalgia: a randomized controlled trial

Table 3 Cost-utility analyses

Alternatives	Usual care	Usual care plus exercise
EQ-5D utility at baseline^a	0.331 (0.150 to 0.511)	0.316 (0.162 to 0.470)
EQ-5D utility at 3 months^a	0.334 (0.175 to 0.494)	0.582 (0.434 to 0.729)
EQ-5D utility at 8 months^a	0.334 (0.175 to 0.493)	0.528 (0.380 to 0.675)
QALY over 8 months^b	0.002 (-0.087 to 0.091)	0.133 (0.034 to 0.231)
QALY difference vs. usual care^c		0.131 (0.011 to 0.290)
Health system perspective:
Incremental cost/person (€)		517
Cost-utility (€/QALY)^c		3,947 (1,782 to 47,000)
Societal perspective:
Incremental cost/person (€)		1,032
Cost-utility (€/QALY) ‡		7,878 (3,559 to 93,818)

QALY, quality adjusted life year.
^aMean (95% confidence interval) estimated by analysis of covariance with adjustment for baseline EQ-5D score and then rounded to 3 significant figures; ^bmean (95% confidence interval) using the area under the curve technique; ^cmean (95% confidence interval estimated by bootstrapping) using the area under the curve technique.