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Figure 5 | Arthritis Research & Therapy

Figure 5

From: Dysfunctional interferon-α production by peripheral plasmacytoid dendritic cells upon Toll-like receptor-9 stimulation in patients with systemic lupus erythematosus

Figure 5

Expression of IFN-α signature genes. Expression of the interferon (IFN)-α responsive genes (a) IFI44, (b) IFIT1, and (c) PRKR was assessed using semiquantitative reverse transcription PCR. Peripheral blood mononuclear cells (PBMCs) were isolated from patients with systemic lupus erythematosus (n = 27; 9 with active and 18 with inactive disease) and healthy control individuals (n = 17). The expression of each gene is presented relative to β-actin expression. The solid bars represent the mean value for each experimental group. Statistical significance was analyzed using Student's t-test.

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