Advertisement
Table 2 MBL concentrations and MBL2 genotypes
| Control individuals | All JRA patients | JRA subgroups | ||
|---|---|---|---|---|
| Polyarthritis | Oligoarthritis | |||
| Exon 1 mutations | ||||
| Sum A/A | 120 (62) | 128 (59) | 43(64) | 85 (56) |
| Sum A/O | 65 (33) | 81 (37) | 22 (33) | 59 (39) |
| A/B | 40 (21) | 43 (20) | 14 (21) | 29 (19) |
| A/C | 5 (3) | 7 (3) | 0 (0) | 7 (5) |
| A/D | 20 (10) | 31 (14) | 8 (12) | 23 (15) |
| Sum O/O | 9 (5) | 9 (4) | 2 (2) | 7 (5) |
| B/B | 4 (2) | 4 (2) | 1 (1) | 3 (2) |
| B/C | 1 (0) | 0 (0) | 0 (0) | 0 (0) |
| B/D | 2 (1) | 3 (1) | 1 (1) | 2 (1) |
| C/D | 0 (0) | 1 (0) | 0 (0) | 1 (1) |
| D/D | 2 (1) | 1 (0) | 0 (0) | 1 (1) |
| Total | 194 (100) | 218 (100) | 67 (100) | 151 (100) |
| Genotype groups | ||||
| High | 110 (57) | 113 (52) | 36 (54) | 77 (51) |
| YA/YA | 60 (31) | 62 (28) | 21 (31) | 41 (27) |
| YA/XA | 50 (26) | 51 (23) | 15 (22) | 36 (24) |
| Medium | 52 (27) | 71 (33) | 23 (34) | 48 (32) |
| XA/XA | 10 (5) | 15 (7) | 7 (10) | 8 (5) |
| YA/O | 42 (22) | 56 (26) | 16 (24) | 40 (27) |
| Low | 32 (16) | 34 (16) | 8 (12) | 26 (17) |
| XA/O | 23 (12) | 25 (12) | 6 (9) | 19 (13) |
| O/O | 9 (4) | 9 (4) | 2 (3) | 7 (5) |
| Total | 194 (100) | 218 (100) | 67 (100) | 151 (100) |
| MBL concentration | ||||
| High | 1.65 (1.20 to 2.69) | 1.86 (1.23 to 3.26) | 1.87 (1.14 to 3.15) | 1.85 (1.32 to 3.67) |
| Medium | 0.52 (0.40 to 0.92) | 0.77 (0.38 to 1.41) | 0.89 (0.32 to 1.79) | 0.73 (0.38 to 1.43) |
| Low | 0.04 (0.02 to 0.13) | 0.07 (0.04 to 0.15) | 0.10 (0.05 to 0.15) | 0.07 (0.04 to 0.17) |
