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Figure 3 | Arthritis Research & Therapy

Figure 3

From: Systemic TNF blockade does not modulate synovial expression of the pro-inflammatory mediator HMGB1 in rheumatoid arthritis patients – a prospective clinical study

Figure 3

Change of HMGB1 synovial mRNA expression before and after infliximab therapy. HMGB1 mRNA expression as determined by reverse-transcriptase PCR for six patients. Values are expressed as fold-change of up- or down-regulation using a log2-scale. The last bar to the right represents the average value for the whole group and the standard deviation is indicated by whiskers.

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