Resting CD4+effector memory T cells are precursors of bystander-activated effectors: a surrogate model of rheumatoid arthritis synovial T-cell function

Table 2 Relationship between day 8 Tck phenotype (MFI) and effector function (TNF-α production from co-cultured monocytes)

Cell phenotype	n	r (correlation)	P
CD25	40	-0.2558	NS
CD69	41	0.00053	NS
HLA-DR	15	0.4094	NS
CD62L	31	-0.4652	0.00084
CD18	21	0.1442	NS
CD29	35	0.2167	NS
CD49d	42	0.3314	0.032
CCR7	42	-0.1711	NS
CXCR4	21	-0.13	NS
CXCR3	21	0.02341	NS
CCR5	21	-0.3948	NS

Day 8 expression of cell surface markers (mean fluorescence intensity [MFI]) was correlated with effector function (tumour necrosis factor [TNF]-α production from monocytes in cytokine-activated T [Tck] cell:monocyte co-culture) using nonparametric (Spearman) correlation analysis. Results are expressed as correlation values (r) and level of significance.

ISSN: 1478-6362