Table 1 Comparison of definitions of metabolic syndrome
From: Metabolic syndrome in rheumatic diseases: epidemiology, pathophysiology, and clinical implications
World Health Organization | National Cholesterol Education Program | International Diabetes Federation |
|---|---|---|
Diabetes or impaired fasting glycemia orimpaired glucose tolerance or insulin resistance (hyperinsulinemic, euglycemic clamp-glucose uptake in lowest 25%) |  | Central obesity: waist circumference ≥ 94 cm (male) or ≥ 80 cm (female)a, or ≥ 90 cm (male) or ≥ 80 cm (female)b |
Plus two or more of the following | Three or more of the following | Plus two or more of the following |
Obesity: body mass index >30 or waist-to-hip ratio >0.9 (male) or >0.85 (female) | Central obesity: waist circumference >102 cm (male) or >88 cm (female) | Fasting plasma glucose ≥ 5.6 mmol/L or medication |
Dyslipidemia: triglycerides ≥ 1.7 mmol/L or HDL cholesterol <0.9 mmol/L (male) or <1.0 mmol/L (female) | Hypertriglyceridemia: triglycerides ≥ 1.7 mmol/L | Hypertriglyceridemia: triglycerides ≥ 1.7 mmol/L or medication |
Hypertension: blood pressure ≥ 140/90 mm Hg | Low HDL cholesterol: <1.0 mmol/L (male)or <1.3 mmol/L (female) | Low HDL cholesterol: <1.0 mmol/L (male) or <1.3 mmol/L (female) or medication |
Microalbuminuria: albumin excretion >20 μg/minute | Hypertension: blood pressure ≥ 130/85 mm Hg | Hypertension: blood pressure ≥ 130/85 mm Hg or medication |
|  | Fasting plasma glucose ≥ 6.1 mmol/L |  |