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Table 1 Comparison of definitions of metabolic syndrome

From: Metabolic syndrome in rheumatic diseases: epidemiology, pathophysiology, and clinical implications

World Health Organization National Cholesterol Education Program International Diabetes Federation
Diabetes or impaired fasting glycemia orimpaired glucose tolerance or insulin resistance (hyperinsulinemic, euglycemic clamp-glucose uptake in lowest 25%)   Central obesity: waist circumference ≥ 94 cm (male) or ≥ 80 cm (female)a, or ≥ 90 cm (male) or ≥ 80 cm (female)b
Plus two or more of the following Three or more of the following Plus two or more of the following
Obesity: body mass index >30 or waist-to-hip ratio >0.9 (male) or >0.85 (female) Central obesity: waist circumference >102 cm (male) or >88 cm (female) Fasting plasma glucose ≥ 5.6 mmol/L or medication
Dyslipidemia: triglycerides ≥ 1.7 mmol/L or HDL cholesterol <0.9 mmol/L (male) or <1.0 mmol/L (female) Hypertriglyceridemia: triglycerides ≥ 1.7 mmol/L Hypertriglyceridemia: triglycerides ≥ 1.7 mmol/L or medication
Hypertension: blood pressure ≥ 140/90 mm Hg Low HDL cholesterol: <1.0 mmol/L (male)or <1.3 mmol/L (female) Low HDL cholesterol: <1.0 mmol/L (male) or <1.3 mmol/L (female) or medication
Microalbuminuria: albumin excretion >20 μg/minute Hypertension: blood pressure ≥ 130/85 mm Hg Hypertension: blood pressure ≥ 130/85 mm Hg or medication
  Fasting plasma glucose ≥ 6.1 mmol/L  
  1. aEuropeans, Sub-Saharan Africans, and Eastern Mediterranean and Middle East (Arab) populations; bSouth Asians and Ethnic South and Central Americans. HDL, high-density lipoprotein.