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Table 1 Characteristics of RA cases at diagnosis of RA

From: Genetic polymorphisms in PTPN22, PADI-4, and CTLA-4 and risk for rheumatoid arthritis in two longitudinal cohort studies: evidence of gene-environment interactions with heavy cigarette smoking

Characteristic

NHS (n = 388)

NHSII (n = 49)

Age at diagnosis (mean ± SD)

57 ± 9

43 ± 5

Rheumatoid factor positive (n [%])

223 (57%)

27 (55%)

Rheumatoid nodules (n [%])

51 (13%)

6 (12%)

Radiographic changes (n [%])

117 (30%)

17 (35%)

Diagnosed by a member of ACR (n [%])

320(84%)

47 (96%)

Mean number of ACR criteria for RA [44], (SD)

5 ± 1

5 ± 1

  1. ACR, American College of Rheumatology; NHS, Nurses' Health Study; RA, rheumatoid arthritis; SD, standard deviation.