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Figure 2 | Arthritis Research & Therapy

Figure 2

From: Characteristics of T-cell large granular lymphocyte proliferations associated with neutropenia and inflammatory arthropathy

Figure 2

Flow cytometric analyses of patient 15 with T-cell large granular lymphocyte leukemia. (a) CD8+CD4- leukemic cells. (b) CD3+/CD45RA+ leukemic cells. (c) CD2+/CD7- leukemic cells and double-stained population in the region R2 consistent with normal T lymphocytes. (d) CD5-/CD25- leukemic cells and CD5+/CD25-/+ expression on normal T lymphocytes in the region R3. (e) CD7- leukemia cells express slightly weaker levels of CD43 compared with normal CD43+higherCD7+ cells consistent with normal T lymphocytes in the region R2. (f) CD3+ population with coexistence of CD16 antigens. (g) CD3+CD56- leukemic cells. (h) CD2+CD57- leukemic cells. CD2+CD57+-reactive T lymphocytes in the region R2. (i) Leukemic cells are positive for CD3 and TCRαβ. FITC, fluorescein isothiocyanate; PE, phycoerythrin; TCR, T-cell receptor.

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Arthritis Research & Therapy

ISSN: 1478-6362

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