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Table 2 Hematological data and T-cell receptor and immunoglobulin gene rearrangements

From: Characteristics of T-cell large granular lymphocyte proliferations associated with neutropenia and inflammatory arthropathy

Case

Hemoglobin, g/dL

WBC, × 109/L

Absolute neutrophil count, × 109/L

Absolute lymphocyte count, × 109/L

Absolute LGL count, × 109/L

Platelet count, × 109/L

TCR and IG gene rearrangements

1

14.1

2.4

0.31

2.0

1.4

204

Vβ-Jβ2, Vγ If, Vγ10-Jγ, Vγ9, Vγ11-Jγ

2

14.6

7.6

0.22

7.1

4.6

148

Vβ-Jβ1, Jβ2, Vβ-Jβ2, Vγ If, Vγ10-Jγ

3

11.3

1.6

0.05

1.3

0.9

103

ND

4

8.2

15.7

1.45

12.9

11.4

381

Vβ-Jβ1, Jβ2, Vβ-Jβ2, Dβ1, Dβ2-Jβ, Vγ If, Vγ10-Jγ, Vγ9, Vγ11-Jγ Vκ-Jκ

5

13.4

9.2

1.5

6.6

4.1

230

Dβ1, Dβ2-Jβ, Vγ If, Vγ10-Jγ, Vδ, Dδ2-Jδ, Dδ3 (biclonal)

6

10.6

2.4

0.31

1.6

1.1

234

Vβ-Jβ1, Jβ2, Dβ1, Dβ2-Jβ, Vγ If, Vγ10-Jγ

7

14.1

1.1

0.15

0.8

0.75

113

Vγ If, Vγ10-Jγ, Vγ9, Vγ11-Jγ, Vδ, Dδ2-Jδ, Dδ3 Vκ, intron-Kde; Vλ-Jλ

8

11.4

2.6

0.39

1.8

0.9

100

Vβ-Jβ1, Jβ2, Dβ1, Dβ2-Jβ

9

11.9

0.9

0.09

0.8

0.5

98

Vβ-Jβ1, Jβ2, Vβ-Jβ2 Vκ-Jκ; Vκ, intron-Kde (biclonal or biallelic); Vλ-Jλ

10

12.1

1.3

0.14

0.8

0.3

112

No rearrangement

11

10.8

1.2

0.06

1.02

0.4

321

No rearrangement

12

9.7

8.7

0.12

7.9

7.1

192

Vβ-Jβ1, Jβ2, Dβ1Dβ2-Jβ (biclonal or biallelic), Vγ If Vγ10-Jγ

13

12.2

8.52

0.72

6.9

6.5

301

Vβ-Jβ1, Jβ2, Dβ1, Dβ2-Jβ, Vγ If, Vγ10-Jγ (biclonal or bliallelic)

14

7.8

7.7

0.8

6.3

4.5

21

ND

15

10.9

17.8

0.71

16.4

11.8

285

Vβ-Jβ1, Jβ2, Dβ1, Dβ2-Jβ (biclonal or biallelic), Vγ If, Vγ10-Jγ, Vγ9, Vγ11-Jγ (biclonal or biallelic) Vκ-Jκ

16

13.0

8.9

0.35

8.5

4.6

200

Vβ-Jβ1, Jβ2, Vβ-Jβ2, Dβ1, Dβ2-Jβ, Vγ If, Vγ10-Jγ, Vγ9, Vγ11-Jγ

17

14.4

2.65

0.10

2.4

2.0

115

Dβ1, Dβ2-Jβ

18

14.9

36.4

0.66

34.5

26.9

57

Vβ-Jβ1, Jβ2, Vβ-Jβ2, Dβ1, Dβ2-Jβ, Vγ9, Vγ11-Jγ, Vδ, Dδ2-Jδ, Dδ3 (biclonal or biallelic)

19

10.2

9.6

0.85

8.4

5.7

154

Vβ-Jβ1, Jβ2, Vβ-Jβ2, Vγ If, Vγ10-Jγ Vγ9, Vγ11-Jγ, Vδ, Dδ2-Jδ, Dδ3

20

9.5

8.5

0.52

7.2

5.4

220

Vβ-Jβ1, Jβ2, Vβ-Jβ2, Vγ If, Vγ10-Jγ

21

4.5

4.5

0.74

3.7

2.1

228

Vβ-Jβ1, Jβ2, (biclonal or biallelic), Vβ-Jβ2 Vγ If, Vγ10-Jγ (biclonal or biallelic)

  1. IG, immunoglobulin; LGL, large granular lymphocyte; ND, not done; TCR, T-cell receptor; WBC, white blood cells.