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Table 1 Regression analysis of membrane n-3 LCPUFA content versus lymphocyte subpopulationa numbers and cytokine production

From: Leukocyte numbers and function in subjects eating n-3 enriched foods: selective depression of natural killer cell levels

 

EPA

DHA

n-3 LCPUFAc

 

r b

p valueb

r

p value

r

p value

CD3+

-0.32

0.07

-0.06

0.74

-0.20

0.27

CD4+

-0.34

0.06

-0.04

0.84

-0.19

0.28

CD8+

-0.17

0.36

-0.07

0.70

-0.12

0.50

CD4+:CD8+

0.14

0.45

0.01

0.94

0.06

0.73

CD16+CD56+

-0.39 d

0.025

-0.37

0.033

-0.38

0.029

CD19+

-0.13

0.47

-0.11

0.56

-0.12

0.50

IFNγ

0.17

0.43

0.13

0.56

0.16

0.50

IL-2

0.23

0.30

0.23

0.30

0.26

0.24

LT

0.43

0.046

0.18

0.44

0.27

0.22

Lymphocytes

-0.45

0.009

-0.21

0.25

-0.28

0.11

Neutrophils

-0.24

0.18

-0.31

0.065

-0.31

0.078

Monocytes

0.06

0.80

0.41

0.11

0.28

0.27

Total leukocytes

-0.33

0.06

-0.32

0.07

-0.34

0.06

  1. aCD3+, all circulating T cells; CD4+, all T helper cells; CD8+, all cytotoxic T cells; CD19+, all B lymphocytes; CD16+CD56+, all NK cells; IFNγ, interferon-gamma; IL-2, interleukin 2; LT, lymphotoxin. bThe correlation coefficient r value; the p value shows the significance (p < 0.05) (ANOVA) of the obtained r value. cn-3 LCPUFA refers to the sum of docosapentaenoic acid (DPA), eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). dBoldfaced text shows results with r value of p < 0.05.
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Arthritis Research & Therapy

ISSN: 1478-6362

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