Skip to main content
Figure 2 | Arthritis Research & Therapy

Figure 2

From: DREAM is reduced in synovial fibroblasts of patients with chronic arthritic pain: is it a suitable target for peripheral pain management?

Figure 2

Relative DREAM gene expression in peripheral blood mononuclear cells from osteoarthritis (OA) patients and healthy controls. Relative gene expression was normalized to GAPDH (glyceraldehyde-3-phosphate dehydrogenase) and is given as delta CT (dCT) value, with higher values representing lower expression levels. DREAM gene expression was significantly lower in OA patients with a high pain score (visual analog scale [VAS] score of greater than 40; ) compared with healthy controls () and with OA patients with a low pain score (VAS score of less than or equal to 40; ). No significant differences were observed between healthy controls and OA patients with a VAS score of less than or equal to 40. Statistics: one-way analysis of variance followed by Tukey's honest significant difference (*P < 0.05). Ctrl, control; DREAM, downstream regulatory element antagonist modulator.

Back to article page