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Figure 3 | Arthritis Research & Therapy

Figure 3

From: DREAM is reduced in synovial fibroblasts of patients with chronic arthritic pain: is it a suitable target for peripheral pain management?

Figure 3

Specific downregulation of DREAM mRNA expression. (a) The effect of five different small interfering RNAs (siRNAs) tested. All show an overall reduction in DREAM expression of 70% to 90% compared with the expression in mock-transfected cells and cells transfected with siRNA-green fluorescence protein (100%). (b) Time course of reduced levels of DREAM expression in synovial fibroblast-like cells transfected with siRNA3 and siRNA4 and incubated 24, 48, and 72 hours. DREAM, downstream regulatory element antagonist modulator.

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Arthritis Research & Therapy

ISSN: 1478-6362

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