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Table 3 Cross-sectional associations at the 10-year follow-up between NT-proBNP (dependent variable) and rheumatoid arthritis disease activity, controlling for cardiovascular risk factors

From: The association between disease activity and NT-proBNP in 238 patients with rheumatoid arthritis: a 10-year longitudinal study

  Adjusted linear regression Multivariate linear regression
  β coefficients P value β coefficients P value
Age 1.04 (1.03–1.05) < 0.001 1.04 (1.03–1.05) < 0.001
Male gender 0.92 (0.64–1.31) 0.64 0.76 (0.53–1.04) 0.09
Body mass indexa 0.96 (0.93–0.98) 0.001   
Atherogenic indexa 0.95 (0.86–1.04) 0.25   
Creatininea 1.02 (1.01–1.02) 0.001 1.01 (1.00–1.02) 0.04
C-reactive proteina 1.01 (1.0–1.03) 0.06 1.02 (1.00–1.02) 0.03
RF IgM-positivea, b 0.92 (0.72–1.19) 0.53   
Anti-CCP-positivea, b 1.14 (0.88–1.45) 0.33   
Ritchie scorea 1.00 (0.99–1.01) 0.87   
DAS28a 1.05 (0.96–1.16) 0.27   
HAQa 1.15 (0.94–1.41) 0.17   
Sharp scorea 1.002 (1.00–1.01) 0.17   
Disease durationa 1.14 (1.02–1.27) 0.02 1.15 (1.03–1.27) 0.01
R2 adjusted    0.38 < 0.001
  1. aAge- and gender-adjusted; bdichotomized variable. anti-CCP, anti-cyclic citrullinated peptide antibody; DAS28, disease activity score of 28 joints; HAQ, Stanford Health Assessment Questionnaire; NT-proBNP, N-terminal pro-brain natriuretic peptide; RF, rheumatoid factor; Ritchie score, Ritchie articular index; Sharp score, van der Heijde modified Sharp criteria.
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