Skip to main content

Table 3 Cross-sectional associations at the 10-year follow-up between NT-proBNP (dependent variable) and rheumatoid arthritis disease activity, controlling for cardiovascular risk factors

From: The association between disease activity and NT-proBNP in 238 patients with rheumatoid arthritis: a 10-year longitudinal study

 

Adjusted linear regression

Multivariate linear regression

 

β coefficients

P value

β coefficients

P value

Age

1.04 (1.03–1.05)

< 0.001

1.04 (1.03–1.05)

< 0.001

Male gender

0.92 (0.64–1.31)

0.64

0.76 (0.53–1.04)

0.09

Body mass indexa

0.96 (0.93–0.98)

0.001

  

Atherogenic indexa

0.95 (0.86–1.04)

0.25

  

Creatininea

1.02 (1.01–1.02)

0.001

1.01 (1.00–1.02)

0.04

C-reactive proteina

1.01 (1.0–1.03)

0.06

1.02 (1.00–1.02)

0.03

RF IgM-positivea, b

0.92 (0.72–1.19)

0.53

  

Anti-CCP-positivea, b

1.14 (0.88–1.45)

0.33

  

Ritchie scorea

1.00 (0.99–1.01)

0.87

  

DAS28a

1.05 (0.96–1.16)

0.27

  

HAQa

1.15 (0.94–1.41)

0.17

  

Sharp scorea

1.002 (1.00–1.01)

0.17

  

Disease durationa

1.14 (1.02–1.27)

0.02

1.15 (1.03–1.27)

0.01

R2 adjusted

  

0.38

< 0.001

  1. aAge- and gender-adjusted; bdichotomized variable. anti-CCP, anti-cyclic citrullinated peptide antibody; DAS28, disease activity score of 28 joints; HAQ, Stanford Health Assessment Questionnaire; NT-proBNP, N-terminal pro-brain natriuretic peptide; RF, rheumatoid factor; Ritchie score, Ritchie articular index; Sharp score, van der Heijde modified Sharp criteria.