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Table 4 Mixed model repeated measure linear regression showing the association between NT-proBNP (dependent variable) and markers of disease activity and treatment

From: The association between disease activity and NT-proBNP in 238 patients with rheumatoid arthritis: a 10-year longitudinal study

  Adjusted linear regression (CI) Multivariate linear regression (CI)
  β coefficients (CI) P value β coefficients (CI) P value
Age 1.03 (1.02–1.03) < 0.001 1.02 (1.01–1.02) < 0.001
Male gender 0.81 (0.64–1.01) 0.06 0.12 (0.05–0.26) < 0.001
C-reactive proteina 1.01 (1.01–1.02) < 0.001 1.01 (1.01–1.02) < 0.001
HAQa 1.12 (1.00–1.27) 0.06   
Prednisolonea, b 1.20 (1.03–1.41) 0.02   
NSAIDa, b 0.90 (0.79–1.04) 0.14   
DMARDa, b 0.95 (0.83–1.09) 0.49   
Sharp scorea 1.01 (1.00–1.01) 0.001   
Ritchie scorea 1.01 (1.00–1.02) 0.01   
Time 1.04 (1.03–1.06) < 0.001 1.03 (1.02–1.05) < 0.001
Time × male gender    1.04 (1.01–1.07) 0.01
Age × male gender    1.03 (1.02–1.05) 0.01
  1. aAge- and gender-adjusted; bdichotomized variable. CI, confidence interval; DMARD, disease-modifying anti-rheumatic drug; HAQ, Stanford Health Assessment Questionnaire; NSAID, non-steroidal anti-inflammatory drug; NT-proBNP, N-terminal pro-brain natriuretic peptide; Ritchie score, Ritchie articular index; Sharp score, van der Heijde modified Sharp criteria.
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