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Figure 1 | Arthritis Research & Therapy

Figure 1

From: Diacerein inhibits the synthesis of resorptive enzymes and reduces osteoclastic differentiation/survival in osteoarthritic subchondral bone: a possible mechanism for a protective effect against subchondral bone remodelling

Figure 1

Representative immunohistochemical staining section for (a) metalloprotease-13 (MMP-13) and (b) cathepsin K in human osteoarthritis subchondral bone. MMP-13 was detected in the osteoblasts (Ob) as well as in the osteoclasts (Oc). Cathepsin K was detected only in osteoclasts. Original magnification, ×100.

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