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Table 1 Cloned alternative splice variant mRNAs

From: Novel splice variants derived from the receptor tyrosine kinase superfamily are potential therapeutics for rheumatoid arthritis

Receptor (n = 21)

NCBI accession number

Novel alternative splice variants

VEGFR1

NM_002019

2

VEGFR2

NM_002253

1

VEGFR3

NM_002020

3

Met

NM_000246

15

Ron

NM_002447

4

Tie1

NM_005424

5

Tie2

NM_000459

2

CSF1R

NM_005211

1

Kit

NM_000222

1

PDGFRβ

NM_002609

1

FGFR1

M34641

2

FGFR2

NM_000141

4

FGFR4

NM_002011

2

EPHA1

NM_005232

2

EPHA2

NM_004431

1

EPHB1

NM_004441

1

EPHB4

NM_004444

3

IGFR1

NM_000875

2

DDR1

NM_013993

2

TNFR1β

NM_001066

1

RAGE

NP_001127

5

Total

 

60

  1. Sixty novel alternative splice variants were cloned from 21 cell surface receptor genes by RT-PCR amplification followed by extensive colony screening. The number of novel alternative splice variants is presented for each receptor tested. NCBI, National Center for Biotechnology Information.