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Table 3 Significant predictors of end-stage renal disease (ESRD) in a cohort of 37 patients with lupus nephritis

From: The renal metallothionein expression profile is altered in human lupus nephritis

Variable

Number of ESRD patients/total number of patients

Patient-years

ESRD rate/1,000 patient-years

Rate ratio

P valuea

Tubular MT scoreb

     

   < 1.0

6/16

79

75.9

6.2

0.03

   ≥ 1.0

1/21

82

12.1

1.0

 

Chronicity index score

     

   < 4

4/30

137

29.2

1

0.04

   ≥ 4

3/7

24

125

4.2

 

Interstitial fibrosis

     

   < 2

4/31

143.5

27.8

1

0.008

   ≥ 2

3/6

17.5

171.4

6.1

 
  1. aLog-rank test. bMetallothionein score as defined in the text.