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Table 4 Genotype frequencies of the genes involved in the IL-4/IL-13 pathway and modified Larsen score

From: Lack of association or interactions between the IL-4, IL-4Rα and IL-13 genes, and rheumatoid arthritis

Gene SNP Genotypes Patients (n) Median LSa P
IL-13 rs1800925 TT 26 31.0  
   CT 271 27.0 0.8
   CC 608 28.0  
  rs1295686 TT 26 33.5  
   CT 251 25.0 0.8
   CC 580 28.0  
IL-4 rs2227284 AA 56 27.0  
   AC 316 29.0 0.6b
   CC 541 29.0  
  rs2243263 CC 8 41.5  
   AC 146 26.0 0.3
   AA 738 28.0  
  rs2243267 CC 18 23.5  
   CG 218 29.0 0.9
   GG 672 28.0  
IL-4R rs1805010 GG 198 24.5  
   AG 460 30.0 0.5
   AA 250 29.0  
  rs1801275 AA 38 28.0  
   AG 316 27.5 0.5
   GG 558 29.0  
  1. aMaximum possible modified (Larsen score) is 160. bBy Cuzick's test for trend. SNP, single nucleotide polymorphism.