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Table 2 Lipid levels and carotid plaque in patients with rheumatic diseases [4750, 5559]

From: Altered lipoprotein metabolism in chronic inflammatory states: proinflammatory high-density lipoprotein and accelerated atherosclerosis in systemic lupus erythematosus and rheumatoid arthritis

  Increase in risk for atherosclerosis Total cholesterol LDL-C HDL-C Triglycerides OxLDL Anti-oxLDL PiHDL Plaque/IMT on carotid ultrasound
SLE OR 7 (general), 50 (females 35 to 44 years old) Normal Normal ↓ or normal Normal ↑↑ ↑ plaque all ages
          Decade 3: 6%
          Decade 4: 13%
          Decade 5: 33%
          Decade 6: 73%
Rheumatoid arthritis 3 ↓ or normal ↓ or normal ↑ plaque all ages
          Decade 3: 7%
          Decade 4: 52%,
          Decade 5: 52%
Psoriatic arthritis 1.6 ↑ or normal ↓ or ↑ Not done Not done Not done Not done ↑ IMT overall
Ankylosing spondylitis 1.6 ↑ or normal Not done Not done Not done Not done ↑ IMT in patients with high BASMI score
Vasculitis Not found Normal Normal Normal Normal Not done Not done ↑ plaque: 58%
  1. ↑, increased; ↑↑, significantly increased; ↓, decreased; BASMI, Bath Ankylosing Spondylitis Metrology Index; HDL-C, high-density lipoprotein cholesterol; IMT, intima-media thickness; LDL-C, low-density lipoprotein cholesterol; OR, odds ratio; oxLDL, oxidized low-density lipoprotein; piHDL, proinflammatory high-density lipoprotein; SLE, systemic lupus erythematosus.