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Figure 4 | Arthritis Research & Therapy

Figure 4

From: Adipose-derived mesenchymal stem cells from the sand rat: transforming growth factor beta and 3D co-culture with human disc cells stimulate proteoglycan and collagen type I rich extracellular matrix

Figure 4

Immunohistochemical documentation of extracellular matrix formed by sand rat adipose-derived mesenchymal stem cells in 3D culture in the presence (b, d) or absence (a, c) of transforming growth factor beta (TGFβ). Note the enhanced keratin sulphate (KS) formed when TGFβ is present (b). Chondroitin sulphate (CS) also was enhanced with TGFβ (d) compared with control (c) × 360. Immunolocalization product is brown.

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