TY - JOUR AU - Pelletier, J. P. AU - Martel-Pelletier, J. AU - Abramson, S. B. PY - 2001 DA - 2001// TI - Osteoarthritis, an inflammatory disease: potential implication for the selection of new therapeutic targets JO - Arthritis Rheum VL - 44 UR - https://doi.org/3.0.CO;2-F DO - 3.0.CO;2-F ID - Pelletier2001 ER - TY - JOUR AU - Hardy, M. M. AU - Seibert, K. AU - Manning, P. T. AU - Currie, M. G. AU - Woerner, B. M. AU - Edwards, D. AU - Koki, A. AU - Tripp, C. S. PY - 2002 DA - 2002// TI - Cyclooxygenase 2-dependent prostaglandin E2modulates cartilage proteoglycan degradation in human osteoarthritis explants JO - Arthritis Rheum VL - 46 UR - https://doi.org/10.1002/art.10356 DO - 10.1002/art.10356 ID - Hardy2002 ER - TY - JOUR AU - Lohmander, L. S. AU - Hoerrner, L. A. AU - Lark, M. W. PY - 1993 DA - 1993// TI - Metalloproteinases, tissue inhibitor, and proteoglycan fragments in knee synovial fluid in human osteoarthritis JO - Arthritis Rheum VL - 36 UR - https://doi.org/10.1002/art.1780360207 DO - 10.1002/art.1780360207 ID - Lohmander1993 ER - TY - JOUR AU - Okada, Y. AU - Shinmei, M. AU - Tanaka, O. AU - Naka, K. AU - Kimura, A. AU - Nakanishi, I. AU - Bayliss, M. T. AU - Iwata, K. AU - Nagase, H. PY - 1992 DA - 1992// TI - Localization of matrix metalloproteinase 3 (storomelysin) in osteoarthritic cartilage and synovium JO - Lab Invest VL - 66 ID - Okada1992 ER - TY - JOUR AU - Nagase, H. PY - 1997 DA - 1997// TI - Activation mechanisms of matrix metalloproteinases JO - Biol Chem VL - 378 ID - Nagase1997 ER - TY - JOUR AU - Tchetverikov, I. AU - Lohmander, L. S. AU - Verzijl, N. AU - Huizinga, T. W. AU - TeKoppele, J. M. AU - Hanemaaijer, R. AU - DeGroot, J. PY - 2005 DA - 2005// TI - MMP protein and activity levels in synovial fluid from patients with joint injury, inflammatory arthritis, and osteoarthritis JO - Ann Rheum Dis VL - 64 UR - https://doi.org/10.1136/ard.2004.022434 DO - 10.1136/ard.2004.022434 ID - Tchetverikov2005 ER - TY - JOUR AU - Szebenyi, G. AU - Fallon, J. F. PY - 1999 DA - 1999// TI - Fibroblast growth factors as multifunctional signaling factors JO - Int Rev Cytol VL - 185 UR - https://doi.org/10.1016/S0074-7696(08)60149-7 DO - 10.1016/S0074-7696(08)60149-7 ID - Szebenyi1999 ER - TY - JOUR AU - Draper, B. W. AU - Stock, D. W. AU - Kimmel, C. B. PY - 2003 DA - 2003// TI - Zebrafish fgf24 functions with fgf8 to promote posterior mesodermal development JO - Development VL - 130 UR - https://doi.org/10.1242/dev.00671 DO - 10.1242/dev.00671 ID - Draper2003 ER - TY - JOUR AU - Tanaka, A. AU - Miyamoto, K. AU - Minamino, N. AU - Takeda, M. AU - Sato, B. AU - Matsuo, H. AU - Matsumoto, K. PY - 1992 DA - 1992// TI - Cloning and characterization of an androgen-induced growth factor essential for the androgen-dependent growth of mouse mammary carcinoma cells JO - Proc Natl Acad Sci USA VL - 89 UR - https://doi.org/10.1073/pnas.89.19.8928 DO - 10.1073/pnas.89.19.8928 ID - Tanaka1992 ER - TY - JOUR AU - MacArthur, C. A. AU - Lawshe, A. AU - Xu, J. AU - Santos-Ocampo, S. AU - Heikinheimo, M. AU - Chellaiah, A. T. AU - Ornitz, D. M. PY - 1995 DA - 1995// TI - FGF-8 isoforms activate receptor splice forms that are expressed in mesenchymal regions of mouse development JO - Development VL - 121 ID - MacArthur1995 ER - TY - JOUR AU - Gemel, J. AU - Gorry, M. AU - Ehrlich, G. D. AU - MacArthur, C. A. PY - 1996 DA - 1996// TI - Structure and sequence of human FGF8 JO - Genomics VL - 35 UR - https://doi.org/10.1006/geno.1996.0349 DO - 10.1006/geno.1996.0349 ID - Gemel1996 ER - TY - JOUR AU - MacArthur, C. A. AU - Lawshe, A. AU - Shankar, D. B. AU - Heikinheimo, M. AU - Shackleford, G. M. PY - 1995 DA - 1995// TI - FGF-8 isoforms differ in NIH3T3 cell transforming potential JO - Cell Growth Differ VL - 6 ID - MacArthur1995 ER - TY - JOUR AU - McKeehan, W. L. AU - Wang, F. AU - Kan, M. PY - 1998 DA - 1998// TI - The heparan sulfate-fibroblast growth factor family: diversity of structure and function JO - Prog Nucleic Acid Res Mol Biol VL - 59 UR - https://doi.org/10.1016/S0079-6603(08)61031-4 DO - 10.1016/S0079-6603(08)61031-4 ID - McKeehan1998 ER - TY - JOUR AU - Ornitz, D. M. AU - Xu, J. AU - Colvin, J. S. AU - McEwen, D. G. AU - MacArthur, C. A. AU - Coulier, F. AU - Gao, G. AU - Goldfarb, M. PY - 1996 DA - 1996// TI - Receptor specificity of the fibroblast growth factor family JO - J Biol Chem VL - 271 UR - https://doi.org/10.1074/jbc.271.25.15292 DO - 10.1074/jbc.271.25.15292 ID - Ornitz1996 ER - TY - JOUR AU - Blunt, A. G. AU - Lawshe, A. AU - Cunningham, M. L. AU - Seto, M. L. AU - Ornitz, D. M. AU - MacArthur, C. A. PY - 1997 DA - 1997// TI - Overlapping expression and redundant activation of mesenchymal fibroblast growth factor (FGF) receptors by alternatively spliced FGF-8 ligands JO - J Biol Chem VL - 272 UR - https://doi.org/10.1074/jbc.272.6.3733 DO - 10.1074/jbc.272.6.3733 ID - Blunt1997 ER - TY - JOUR AU - Ohuchi, H. AU - Yoshioka, H. AU - Tanaka, A. AU - Kawakami, Y. AU - Nohno, T. AU - Noji, S. PY - 1994 DA - 1994// TI - Involvement of androgen-induced growth factor (FGF-8) gene in mouse embryogenesis and morphogenesis JO - Biochem Biophys Res Commun VL - 204 UR - https://doi.org/10.1006/bbrc.1994.2542 DO - 10.1006/bbrc.1994.2542 ID - Ohuchi1994 ER - TY - JOUR AU - Mahmood, R. AU - Bresnick, J. AU - Hornbruch, A. AU - Mahony, C. AU - Morton, N. AU - Colquhoun, K. AU - Martin, P. AU - Lumsden, A. AU - Dickson, C. AU - Mason, I. PY - 1995 DA - 1995// TI - A role for FGF-8 in the initiation and maintenance of vertebrate limb bud outgrowth JO - Curr Biol VL - 5 UR - https://doi.org/10.1016/S0960-9822(95)00157-6 DO - 10.1016/S0960-9822(95)00157-6 ID - Mahmood1995 ER - TY - JOUR AU - Crossley, P. H. AU - Minowada, G. AU - MacArthur, C. A. AU - Martin, G. R. PY - 1996 DA - 1996// TI - Roles for FGF8 in the induction, initiation, and maintenance of chick limb development JO - Cell VL - 84 UR - https://doi.org/10.1016/S0092-8674(00)80999-X DO - 10.1016/S0092-8674(00)80999-X ID - Crossley1996 ER - TY - JOUR AU - Sun, X. AU - Mariani, F. V. AU - Martin, G. R. PY - 2002 DA - 2002// TI - Functions of FGF signalling from the apical ectodermal ridge in limb development JO - Nature VL - 418 UR - https://doi.org/10.1038/nature00902 DO - 10.1038/nature00902 ID - Sun2002 ER - TY - JOUR AU - Valta, M. P. AU - Hentunen, T. AU - Qu, Q. AU - Valve, E. M. AU - Harjula, A. AU - Seppanen, J. A. AU - Vaananen, H. K. AU - Harkonen, P. L. PY - 2006 DA - 2006// TI - Regulation of osteoblast differentiation: a novel function for fibroblast growth factor 8 JO - Endocrinology VL - 147 UR - https://doi.org/10.1210/en.2005-1502 DO - 10.1210/en.2005-1502 ID - Valta2006 ER - TY - JOUR AU - Ishibe, T. AU - Nakayama, T. AU - Okamoto, T. AU - Aoyama, T. AU - Nishijo, K. AU - Shibata, K. R. AU - Shima, Y. AU - Nagayama, S. AU - Katagiri, T. AU - Nakamura, Y. AU - Nakamura, T. AU - Toguchida, J. PY - 2005 DA - 2005// TI - Disruption of fibroblast growth factor signal pathway inhibits the growth of synovial sarcomas: potential application of signal inhibitors to molecular target therapy JO - Clin Cancer Res VL - 11 UR - https://doi.org/10.1158/1078-0432.CCR-04-2057 DO - 10.1158/1078-0432.CCR-04-2057 ID - Ishibe2005 ER - TY - JOUR AU - Kikuchi, T. AU - Yamada, H. AU - Shinmei, M. PY - 1996 DA - 1996// TI - Effect of high molecular weight hyaluronan on cartilage degeneration in a rabbit model of osteoarthritis JO - Osteoarthr Cartil VL - 4 UR - https://doi.org/10.1016/S1063-4584(05)80319-X DO - 10.1016/S1063-4584(05)80319-X ID - Kikuchi1996 ER - TY - JOUR AU - Colombo, C. AU - Butler, M. AU - O' Byrne, E. AU - Hickman, L. AU - Swartzendruber, D. AU - Selwyn, M. AU - Steinetz, B. PY - 1983 DA - 1983// TI - A new model of osteoarthritis in rabbits. I. Development of knee joint pathology following lateral meniscectomy and section of the fibular collateral and sesamoid ligaments JO - Arthritis Rheum VL - 26 UR - https://doi.org/10.1002/art.1780260709 DO - 10.1002/art.1780260709 ID - Colombo1983 ER - TY - JOUR AU - Tanaka, A. AU - Furuya, A. AU - Yamasaki, M. AU - Hanai, N. AU - Kuriki, K. AU - Kamiakito, T. AU - Kobayashi, Y. AU - Yoshida, H. AU - Koike, M. AU - Fukayama, M. PY - 1998 DA - 1998// TI - High frequency of fibroblast growth factor (FGF) 8 expression in clinical prostate cancers and breast tissues, immunohistochemically demonstrated by a newly established neutralizing antibody against FGF 8 JO - Cancer Res VL - 58 ID - Tanaka1998 ER - TY - JOUR AU - Shimada, N. AU - Ishii, T. AU - Imada, T. AU - Takaba, K. AU - Sasaki, Y. AU - Maruyama-Takahashi, K. AU - Maekawa-Tokuda, Y. AU - Kusaka, H. AU - Akinaga, S. AU - Tanaka, A. AU - Shitara, K. PY - 2005 DA - 2005// TI - A neutralizing anti-fibroblast growth factor 8 monoclonal antibody shows potent antitumor activity against androgen-dependent mouse mammary tumors in vivo JO - Clin Cancer Res VL - 15 UR - https://doi.org/10.1158/1078-0432.CCR-04-2358 DO - 10.1158/1078-0432.CCR-04-2358 ID - Shimada2005 ER - TY - JOUR AU - Janusz, M. J. AU - Hookfin, E. B. AU - Heitmeyer, S. A. AU - Woessner, J. F. AU - Freemont, A. J. AU - Hoyland, J. A. AU - Brown, K. K. AU - Hsieh, L. C. AU - Almstead, N. G. AU - De, B. AU - Natchus, M. G. AU - Pikul, S. AU - Taiwo, Y. O. PY - 2001 DA - 2001// TI - Moderation of iodoacetate-induced experimental osteoarthritis in rats by matrix metalloproteinase inhibitors JO - Osteoarthr Cartil VL - 9 UR - https://doi.org/10.1053/joca.2001.0472 DO - 10.1053/joca.2001.0472 ID - Janusz2001 ER - TY - JOUR AU - Kuroki, H. AU - Nakagawa, Y. AU - Mori, K. AU - Ohba, M. AU - Suzuki, T. AU - Mizuno, Y. AU - Ando, K. AU - Takenaka, M. AU - Ikeuchi, K. AU - Nakamura, T. PY - 2004 DA - 2004// TI - Acoustic stiffness and change in plug cartilage over time after autologous osteochondral grafting: correlation between ultrasound signal intensity and histological score in a rabbit model JO - Arthritis Res Ther VL - 6 UR - https://doi.org/10.1186/ar1219 DO - 10.1186/ar1219 ID - Kuroki2004 ER - TY - JOUR AU - Tamura, T. AU - Kosaka, N. AU - Ishiwa, J. AU - Sato, T. AU - Nagase, H. AU - Ito, A. PY - 2001 DA - 2001// TI - Rhein, an active metabolite of diacerein, down-regulates the production of pro-matrix metalloproteinases-1, -3, -9 and -13 and up-regulates the production of tissue inhibitor of metalloproteinase-1 in cultured rabbit articular chondrocytes JO - Osteoarthr Cartil VL - 9 UR - https://doi.org/10.1053/joca.2000.0383 DO - 10.1053/joca.2000.0383 ID - Tamura2001 ER - TY - JOUR AU - Hamilton, J. A. AU - Slywka, J. PY - 1981 DA - 1981// TI - Stimulation of human synovial fibroblast plasminogen activator production by mononuclear cell supernatants JO - J Immunol VL - 126 ID - Hamilton1981 ER - TY - JOUR AU - Chandrasekhar, S. AU - Esterman, M. A. AU - Hoffman, N. A. PY - 1987 DA - 1987// TI - Microdetermination of proteoglycan and glycosaminoglycans in the presence of guanidine hydrochloride JO - Anal Biochem VL - 161 UR - https://doi.org/10.1016/0003-2697(87)90658-0 DO - 10.1016/0003-2697(87)90658-0 ID - Chandrasekhar1987 ER - TY - JOUR AU - Yamada, A. AU - Uegaki, A. AU - Makamura, T. AU - Ogawa, K. PY - 2000 DA - 2000// TI - ONO – an orally active matrix metalloproteinase inhibitor, prevents lipopolysaccharide-induced proteoglycan release from the joint cartilage in guinea pigs JO - Inflamm Res VL - 49 UR - https://doi.org/10.1007/s000110050573 DO - 10.1007/s000110050573 ID - Yamada2000 ER - TY - JOUR AU - Schrier, D. J. AU - Flory, C. M. AU - Finkel, M. AU - Kuchera, S. L. AU - Lesch, M. E. AU - Jacobson, P. B. PY - 1996 DA - 1996// TI - The effects of the phospholipase A2inhibitor, manoalide, on cartilage degradation, stromelysin expression, and synovial fluid cell count induced by intraarticular injection of human recombinant interleukin-1 in the rabbit JO - Arthritis Rheum VL - 39 UR - https://doi.org/10.1002/art.1780390805 DO - 10.1002/art.1780390805 ID - Schrier1996 ER - TY - JOUR AU - Tamura, T. AU - Nakanishi, T. AU - Kimura, Y. AU - Hattori, T. AU - Sasaki, K. AU - Norimatsu, H. AU - Takahashi, K. AU - Takigawa, M. PY - 1996 DA - 1996// TI - Nitric oxide mediates interleukin-1-induced matrix degradation and basic fibroblast growth factor release in cultured rabbit articular chondrocytes: a possible mechanism of pathological neovascularization in arthritis JO - Endocrinology VL - 137 ID - Tamura1996 ER - TY - JOUR AU - Evans, C. H. AU - Georgescu, H. I. PY - 1983 DA - 1983// TI - Observations on the senescence of cells derived from articular cartilage JO - Mech Ageing Dev VL - 22 UR - https://doi.org/10.1016/0047-6374(83)90111-2 DO - 10.1016/0047-6374(83)90111-2 ID - Evans1983 ER - TY - JOUR AU - Stove, J. AU - Gerlach, C. AU - Huch, K. AU - Gunther, K. P. AU - Brenner, R. AU - Puhl, W. AU - Scharf, H. P. PY - 2001 DA - 2001// TI - Gene expression of stromelysin and aggrecan in osteoarthritic cartilage JO - Pathobiology VL - 69 UR - https://doi.org/10.1159/000064641 DO - 10.1159/000064641 ID - Stove2001 ER - TY - JOUR AU - Ayral, X. AU - Pickering, E. H. AU - Woodworth, T. G. AU - Mackillop, N. AU - Dougados, M. PY - 2005 DA - 2005// TI - Synovitis a potential predictive factor of structural progression of medial tibiofemoral knee osteoarthritis – results of a 1 year longitudinal arthroscopic study in 422 patients JO - Osteoarthritis Cartilage VL - 13 UR - https://doi.org/10.1016/j.joca.2005.01.005 DO - 10.1016/j.joca.2005.01.005 ID - Ayral2005 ER - TY - JOUR AU - Arner, E. C. AU - Pratta, M. A. PY - 1989 DA - 1989// TI - Independent effects of interleukin-1 on proteoglycan breakdown, proteoglycan synthesis, and prostaglandin E2release from cartilage in organ culture JO - Arthritis Rheum VL - 32 UR - https://doi.org/10.1002/anr.1780320310 DO - 10.1002/anr.1780320310 ID - Arner1989 ER - TY - JOUR AU - Amin, A. R. AU - Attur, M. AU - Patel, R. N. AU - Thakker, G. D. AU - Marshall, P. J. AU - Rediske, J. AU - Stuchin, A. S. AU - Patel, I. R. AU - Abramson, S. B. PY - 1997 DA - 1997// TI - Superinduction of cyclooxygenase-2 activity in human osteoarthritis-affected cartilage: influence of nitric oxide JO - J Clin Invest VL - 99 UR - https://doi.org/10.1172/JCI119280 DO - 10.1172/JCI119280 ID - Amin1997 ER - TY - JOUR AU - Daouti, S. AU - Latario, B. AU - Nagulapalli, S. AU - Buxton, F. AU - Uziel-Fusi, S. AU - Chirn, G. W. AU - Bodian, D. AU - Song, C. AU - Labow, M. AU - Lotz, M. AU - Quintavalla, J. AU - Kumar, C. PY - 2005 DA - 2005// TI - Development of comprehensive functional genomic screens to identify novel mediators of osteoarthritis JO - Osteoarthr Cartil VL - 13 UR - https://doi.org/10.1016/j.joca.2005.02.003 DO - 10.1016/j.joca.2005.02.003 ID - Daouti2005 ER - TY - JOUR AU - Chuma, H. AU - Mizuta, H. AU - Kudo, S. AU - Takagi, K. AU - Hiraki, Y. PY - 2004 DA - 2004// TI - One day exposure to FGF-2 was sufficient for the regenerative repair of full-thickness defects of articular cartilage in rabbits JO - Osteoarthr Cartil VL - 12 UR - https://doi.org/10.1016/j.joca.2004.07.003 DO - 10.1016/j.joca.2004.07.003 ID - Chuma2004 ER - TY - JOUR AU - Kalbhen, D. A. AU - Blum, U. PY - 1977 DA - 1977// TI - Hypothesis and experimental confirmation of a new pharmacological model of osteoarthrosis JO - Arzneimittelforschung VL - 27 ID - Kalbhen1977 ER -