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Table 1 Demographic characteristics of the study subjects

From: Interferon-induced protein IFIT4 is associated with systemic lupus erythematosus and promotes differentiation of monocytes into dendritic cell-like cells

Characteristic SLE patients Healthy donors P
Participants (n) 108 46 -
Age (years) 32.52 ± 11.97 32.5 ± 14.32 0.83
Sex (n; female/male) 96/12 40/6 0.62
Onset age (years) 27.14 ± 10.0 NA -
Disease duration (years) 5.4 ± 4.13 NA -
SLEDAI-2K score (mean [range]) 6 (3 to 8) NA -
Mean ESR (mm/hour) 61.58 ± 24.03 NA -
Medical therapy (n)    
   Prednisone >60 mg/day 11 NA -
   Prednisone 30 to 60 mg/day 44 NA -
   Prednisone 0 mg/day 6 NA -
   CTX 35 NA -
FIT4 relative expression 37.84 ± 3.52 10.58 ± 2.64 0.00
  1. All patients were of Chinese ethnicity. Unless stated otherwise, values are expressed as mean ± standard deviation. CTX, cyclophosphamide; ESR, erythrocyte sedimentation rate; IFIT4, interferon-induced protein with tetratricopeptide repeats 4; NA, not applicable; SLE, systemic lupus erythematosus; SLEDAI-2K, SLE Disease Activity Index 2,000.