Skip to main content

Table 3 Genes with increased expression in synovial fibroblasts from DA.F344 (Cia5d) compared with DA

From: Cia5dregulates a new fibroblast-like synoviocyte invasion-associated gene expression signature

Gene Symbold

Definitiona

Accession number

DA mean

Cia5d mean

Fold change

P valueb

Overall rankc

Cancer, Cell Cycle, DNA replication, recombination and repair

Gadd45b

Growth arrest and DNA-damage-inducible 45 beta

NM_001008321.1

214.12

412.97

1.9

0.00572

39

Gmfg

Glia maturation factor, gamma (Gmfg)

NM_181091.2

1359.39

2261.87

1.7

0.00817

54

Plekhg2_predicted

Pleckstrin homology domain containing, family G (with RhoGef domain) member 2 (predicted)

XM_214862.3

91.97

147.62

1.6

0.00784

52

Lox

Lysyl oxidase

XM_579391.1

15755.11

24559.79

1.6

0.00198

12

Brwd3_predicted

Similar to bromo domain-containing protein disrupted in leukemia (LOC317213)

XM_228518.3

43.85

52.99

1.2

0.00596

43

Aph1a

Similar to anterior pharynx defective 1 homolog A (C. elegans)

XM_345251.2

2820.66

3246.28

1.2

0.00046

4

Pex19_predicted e

Peroxisome biogenesis factor 19 (predicted)

XM_225711.3

119.41

135.98

1.1

0.00561

38

Cell Signaling

       

Fkbp7_predicted

FK506 binding protein 7 (predicted)

XM_215758.3

784.02

1450.53

1.9

0.00578

40

Ncor1

Nuclear receptor co-repressor 1

XM_577103.1

420.35

679.65

1.6

0.00454

32

Tap1

Transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)

NM_032055.1

190.32

288.49

1.5

0.00878

61

Prnp

Prion protein

XM_579340.1

17242.89

24050.29

1.4

0.00029

3

Fzd4

Frizzled homolog 4 (Drosophila)

NM_022623.1

44.45

60.14

1.4

0.00406

26

Gene expression

       

H1f0

H1 histone family, member 0

NM_012578.2

150.12

229.40

1.5

0.00707

47

Cell-Cell Interaction

       

Fath

Hypothetical gene supported by NM_031819; Fath fat tumor suppressor homolog (Drosophila)

XM_579538.1

3803.04

5806.86

1.5

0.00206

13

Extracellular Matrix

       

Col5a1

Collagen, type V, alpha 1 (Col5a1)

NM_134452.1

7240.26

9852.22

1.4

0.00807

53

Others

       

Gtlf3b_predicted

Gene trap locus F3b (predicted)

XM_343907.2

78.16

175.41

2.2

0.00003

1

Olfml2b_predicted

Olfactomedin-like 2B (predicted)

XM_222868.3

1336.30

2949.43

2.2

0.00241

17

Gsdmdc1_predicted

Gasdermin domain containing 1 (predicted)

XM_235434.3

458.74

831.39

1.8

0.00295

20

Trim41_predicted

Tripartite motif-containing 41 (predicted)

XM_220357.3

422.66

732.37

1.7

0.00100

7

LOC498815

Hypothetical gene supported by AY771707

XM_579873.1

243.56

366.68

1.5

0.00281

19

LOC304860

Similar to N-acetylneuraminate pyruvate lyase

XM_222736.3

270.64

401.65

1.5

0.00176

11

Setdb2_predicted

SET domain, bifurcated 2 (predicted)

XM_224248.3

94.38

136.31

1.4

0.00945

66

LOC361448

Similar to cDNA sequence BC013529 (predicted)

XM_341726.2

2852.12

4043.46

1.4

0.00071

5

LOC360899

Similar to SERTA domain containing 4

XM_341174.2

1771.29

2489.20

1.4

0.00886

63

Ormdl2_predicted

ORM1-like 2 (S. cerevisiae) (predicted)

XM_213832.3

1996.56

2773.15

1.4

0.00549

37

LOC498067

Similar to RIKEN cDNA 2310003P10 (LOC498067), mRNA.

XM_573266.1

368.00

494.10

1.3

0.00860

58

Nit1

Nitrilase 1

NM_182668.1

3397.58

4472.84

1.3

0.00296

21

Fam18b_predicted

Family with sequence similarity 18, member B (predicted)

XM_219680.3

2915.92

3746.20

1.3

0.00447

31

Ubxd2_predicted

UBX domain containing 2 (predicted)

XM_573443.1

2018.75

2569.23

1.3

0.00411

27

  1. aEstrogen; ER, estrogen-induced, or estrogen-receptor signaling or degradation are marked in bold. bt test. cOrder (logistic regression) in the list of 66 genes differentially expressed between DA and DA.F344(Cia5d). dCancer and invasion associated genes are in italics. eIncreased expression in invading breast cancers.
Back to article page

Arthritis Research & Therapy

ISSN: 1478-6362

Contact us