Figure 5
Inter-individual mRNA expression variances in the complex of apoptosis in rheumatoid arthritis (RA) compared with normal control (NC). The graph shows genes affected by significant intra-group inter-individual mRNA expression variances in RA compared with NC (P ≤ 0.05; Bonferroni/Holm corrected Brown-Forsythe version of the Levene test; labeled in red) in the Kyoto Encyclopedia of Genes and Genomes (KEGG) complex of apoptosis. Among the three apoptosis sub-complexes, the survival factor-dependent sub-complex was significantly affected by gene expression variances (P ≤ 0.15, χ2 test; indicated in red). Cellular processes with potential influence on or relevance for RA pathogenesis (expression of survival genes and cell survival) are labeled in blue.