Figure 7From: Expression and regulation of neurotrophins in the nondegenerate and degenerate human intervertebral discEffect of proinflammatory cytokines on neurotrophin and neuropeptide gene expression in nucleus pulposus cells. Histograms illustrating the relative gene expression of (a) nerve growth factor (NGF), (b) brain-derived neurotrophic factor (BDNF) and (c) substance P in nondegenerate and degenerate nucleus pulposus (NP) cells cultured with IL-1β and TNFα normalised to 18s and untreated controls. *Significance between IL-1β treatment and untreated control, **significance between IL-1β and TNFα treatments (P < 0.05). Data presented as the mean ± standard error of the mean.Back to article page