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Table 3 False-positive report probabilities under different scenarios

From: A polymorphism in the human serotonin 5-HT2A receptor gene may protect against systemic sclerosis by reducing platelet aggregation

Prior probability Odds ratio
  1.5 1.75 2
0.1 0.48 0.29 0.19
0.05 0.66 0.46 0.33
0.01 0.91 0.82 0.72
0.001 0.99 0.98 0.97
  1. False-positive report probability values are presented for the association between the C+1354T single nucleotide polymorphism and systemic sclerosis in our population. Different ranges of values are reported in relation to the prior probability values and the power to detect different odds ratios for 452His/452Tyr individuals compared with 452His/452His subjects, with α = 0.009. Data in italics are reported noteworthy false-positive report probability values at the 0.5 level.