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Table 2 Relevant members of the selectin, integrin, and immunoglobulin adhesion molecule superfamilies

From: Vascular involvement in rheumatic diseases: 'vascular rheumatology'

Adhesion receptors Ligands
   L-selectin (CD62L, LAM-1) Sialylated carbohydrates, GlyCAM-1
   E-selectin (CD62E, ELAM-1) Sialyl-Lewis-X
   P-selectin (CD62P, PADGEM) Sialyl-Lewis-X, other carbohydrates
   β1 integrins Laminin, collagen, fibronectin
   α4β1 integrins Fibronectin, VCAM-1
   β2 integrins ICAM-1, ICAM-2, ICAM-3, JAM-A
   β3 integrins Vitronectin, von Willebrand factor, other matrix molecules
Immunoglobulin superfamily  
   ICAM-1, ICAM-3 αLβ2 (LFA-1), αMβ2 (Mac-1, CR3)
   VCAM-1 α4β1, α4β7
   CD2 LFA-3
   PECAM-1 (CD31) PECAM-1, αVβ3 integrin
  1. ELAM-1, endothelial-leukocyte adhesion molecule-1; GlyCAM-1, glycosylation-dependent cell adhesion molecule-1; ICAM, intracellular adhesion molecule; JAM-A, junctional adhesion molecule-A; LAM-1, leukocyte adhesion molecule-1; LFA, lymphocyte function-associated antigen; Mac-1, macrophage integrin; PADGEM, platelet activation-dependent granule-external membrane protein; PECAM-1, platelet-endothelial cell adhesion molecule-1; VCAM-1, vascular cell adhesion molecule-1.