Skip to main content

Advertisement

Table 3 Chemokine receptors with ligands relevant for arthritis and angiogenesis

From: Vascular involvement in rheumatic diseases: 'vascular rheumatology'

Chemokine receptor Chemokine ligand
CXC chemokine receptors  
   CXCR1 IL-8/CXCL8
   CXCR2 IL-8/CXCL8, ENA-78/CXCL5, groα/CXCL1, CTAP-III/CXCL7
   CXCR3 IP-10/CXCL10, PF4/CXCL4, Mig/CXCL9, ITAC/CXCL11
   CXCR4 SDF-1/CXCL12
C-C chemokine receptors  
   CCR1 MIP-1α/CCL3, RANTES/CCL5, MCP-3/CCL7, MPIF-1/CCL23
   CCR2 MCP-1/CCL2, MCP-3/CCL7
   CCR6 MIP-3α/CCL20
   CCR7 MIP-3β/CCL19, SLC/CCL21
C chemokine receptors  
   XCR1 Lymphotactin/XCL1
C-X3-C chemokine receptors  
   CX3CR1 Fractalkine/CX3CL1
  1. CTAP-III, connective tissue-activating peptide-III; ENA-78, epithelial neutrophil-activating protein-78; groα, growth-regulated oncogene-alpha; IL-8, interleukin-8; IP-10, interferon-gamma-inducible 10-kDa protein; ITAC, interferon-inducible T-cell alpha chemoattractant; MCP, monocyte chemoattractant protein; Mig, monokine induced by interferon-gamma; MIP, macrophage inflammatory protein; MPIF-1, myeloid progenitor inhibitory factor-1; PF4, platelet factor-4; RANTES, Regulated upon Activation, Normal T-cell Expressed and Secreted; SDF-1, stromal cell-derived factor-1; SLC, secondary lymphoid tissue chemokine.