Role of STAT4 polymorphisms in systemic lupus erythematosus in a Japanese population: a case-control association study of the STAT1-STAT4region

Kawasaki, Aya; Ito, Ikue; Hikami, Koki; Ohashi, Jun; Hayashi, Taichi; Goto, Daisuke; Matsumoto, Isao; Ito, Satoshi; Tsutsumi, Akito; Koga, Minori; Arinami, Tadao; Graham, Robert R; Hom, Geoffrey; Takasaki, Yoshinari; Hashimoto, Hiroshi; Behrens, Timothy W; Sumida, Takayuki; Tsuchiya, Naoyuki

doi:10.1186/ar2516

Table 1 Minor allele frequencies and P values for 52 tag single nucleotide polymorphisms in the STAT1-STAT4 region in the first screening

From: Role of STAT4 polymorphisms in systemic lupus erythematosus in a Japanese population: a case-control association study of the STAT1-STAT4region

			Minor allele frequency
SNP	Chromosomal position^a	Minor allele	SLE patients (n = 105)	Controls (n = 102)	P value
rs3771300	191543841	C	0.305	0.309	0.929
rs7575823	191544163	A	0.167	0.147	0.584
rs16824035	191545879	A	0.057	0.074	0.500
rs1914408	191548221	A	0.271	0.314	0.344
rs2066804	191550004	A	0.471	0.480	0.855
rs2280235	191552075	A	0.486	0.471	0.758
rs3755312	191554236	C	0.181	0.176	0.905
rs2280234	191558344	G	0.162	0.186	0.513
rs2280232	191559011	C	0.143	0.123	0.543
rs11887698	191563119	G	0.327	0.304	0.629
rs7562024	191563766	G	0.090	0.108	0.554
rs11904548	191567235	A	0.162	0.137	0.482
rs12693591	191568747	A	0.257	0.235	0.606
rs16833155	191569622	A	0.043	0.054	0.600
rs2066805	191571146	G	0.038	0.054	0.442
rs11677408	191574860	A	0.129	0.108	0.514
rs2030171	191577408	G	0.329	0.309	0.666
rs11693463	191578156	G	0.195	0.196	0.983
rs11885069	191578869	A	0.162	0.137	0.482
rs10199181	191581798	T	0.267	0.265	0.964
rs2066802	191582912	G	0.257	0.255	0.956
rs13029532	191584146	C	0.082	0.103	0.457
rs3024904	191603447	A	0.112	0.141	0.400
rs3024936	191603621	C	0.024	0.055	0.112
rs1517351	191604290	C	0.490	0.464	0.602
rs3024896	191604961	A	0.448	0.412	0.461
rs925847	191605785	A	0.538	0.490	0.330
rs3024886	191608694	A	0.457	0.417	0.407
rs6715106	191621279	G	0.067	0.083	0.520
rs16833215	191622044	G	0.495	0.441	0.270
rs1400654	191623918	T	0.066	0.083	0.524
rs3024861	191632851	T	0.471	0.397	0.127
rs1517352	191639709	A	0.481	0.397	0.086
rs10168266	191644049	A	0.400	0.245	7.6 × 10^-4
rs7594501	191646845	A	0.114	0.152	0.250
rs16833239	191648505	A	0.110	0.152	0.200
rs7601754	191648696	G	0.129	0.178	0.162
rs11889341	191651987	A	0.443	0.299	0.003
rs16833249	191656517	G	0.567	0.480	0.079
rs6434435	191662109	A	0.099	0.141	0.192
rs7574865	191672878	A	0.471	0.324	0.002
rs12463658	191673589	C	0.581	0.471	0.025
rs6752770	191681808	G	0.205	0.245	0.326
rs1551443	191704763	A	0.238	0.206	0.431
rs2356350	191710783	G	0.510	0.407	0.036
rs10189819	191716994	G	0.133	0.118	0.630
rs7596818	191717555	A	0.320	0.295	0.580
rs11685878	191717700	A	0.429	0.431	0.954
rs12991409	191717762	G	0.100	0.113	0.674
rs12327969	191719016	G	0.390	0.402	0.811
rs12988825	191722509	C	0.119	0.132	0.683
rs7572482	191723317	G	0.490	0.461	0.545

^aChromosomal positions are shown according to the National Center for Biotechnology Information (Bethesda, MD, USA) reference assembly. SLE, systemic lupus erythematosus; SNP, single nucleotide polymorphism; STAT, signal transducers and activators of transcription.

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