Table 2 Detailed iloprost infusion scheme. The body weight-dependent dose was increased from day one to day five. At day five and four, the dose was adjusted according to adverse effects. The infusion time was six hours per day
From: Rationale for prostaglandin I2in bone marrow oedema – from theory to application
First day (mL/hour) | Second day (mL/hour) | Third to fifth day (mL/hour) | |
|---|---|---|---|
Body weight (kg) | (0.5 ng/kg/minute) | (0.75 ng/kg/minute) | (1.0 ng/kg/minute) |
60 | 2.2 | 3.4 | 4.5 |
70 | 2.6 | 4.0 | 5.3 |
80 | 3.0 | 4.5 | 6.0 |
90 | 3.4 | 5.1 | 6.8 |
100 | 3.8 | 5.7 | 7.5 |
110 | 4.1 | 6.2 | 8.3 |