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Table 3 Study design to evaluate the therapeutic potential of iloprost over a follow-up of six months. Clinical parameters and MRI evaluation of the patients before and three and six months after iloprost application. X: investigation; -: no investigation

From: Rationale for prostaglandin I2in bone marrow oedema – from theory to application

Follow-up Before treatment (day 0) Day one to five Three months Six months
Clinical parameters     
Visual analogue pain scale X X X X
Harris-Hip-Score X - X X
Knee-Society Score X - X X
SF-36 X - X X
Radiological parameters     
X-rays in two planes X - X X
MRI scans X - X X