Table 3 Study design to evaluate the therapeutic potential of iloprost over a follow-up of six months. Clinical parameters and MRI evaluation of the patients before and three and six months after iloprost application. X: investigation; -: no investigation
From: Rationale for prostaglandin I2in bone marrow oedema – from theory to application
Follow-up | Before treatment (day 0) | Day one to five | Three months | Six months |
|---|---|---|---|---|
Clinical parameters | ||||
Visual analogue pain scale | X | X | X | X |
Harris-Hip-Score | X | - | X | X |
Knee-Society Score | X | - | X | X |
SF-36 | X | - | X | X |
Radiological parameters | ||||
X-rays in two planes | X | - | X | X |
MRI scans | X | - | X | X |