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Table 4 Follow-up of 117 bones affected by bone marrow oedema/avascular osteonecrosis before and three and six months after intravenous iloprost application. There is a significant improvement in Association Research Circulation Osseous (ARCO) I and early ARCO II stages

From: Rationale for prostaglandin I2in bone marrow oedema – from theory to application

 

ARCO 0

ARCO I

ARCO II

ARCO III

ARCO IV

 

Femoral head (n = 42)

Before treatment

0

20

12

9

1

Three months

15

9

8

9

1

Six months

18

8

6

9

1

 

Distal femur (n = 19)

Before treatment

0

13

4

2

0

Three months

10

4

3

2

0

Six months

11

3

3

2

0

 

Proximal tibia (n = 18)

Before treatment

0

14

2

2

0

Three months

10

5

1

2

0

Six months

13

2

1

2

0

 

Distal tibia (n = 7)

Before treatment

0

6

1

0

0

Three months

3

4

0

0

0

Six months

3

4

0

0

0

 

Hindfoot (n = 21)

Before treatment

0

21

0

0

0

Three months

12

8

1

0

0

Six months

14

5

2

0

0

 

Middlefoot (n = 7)

Before treatment

0

7

0

0

0

Three months

6

1

0

0

0

Six months

6

1

0

0

0

 

Humerus (n = 3)

Before treatment

0

1

1

0

1

Three months

0

0

2

0

1

Six months

0

0

2

0

1