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Table 4 Follow-up of 117 bones affected by bone marrow oedema/avascular osteonecrosis before and three and six months after intravenous iloprost application. There is a significant improvement in Association Research Circulation Osseous (ARCO) I and early ARCO II stages

From: Rationale for prostaglandin I2in bone marrow oedema – from theory to application

  ARCO 0 ARCO I ARCO II ARCO III ARCO IV
  Femoral head (n = 42)
Before treatment 0 20 12 9 1
Three months 15 9 8 9 1
Six months 18 8 6 9 1
  Distal femur (n = 19)
Before treatment 0 13 4 2 0
Three months 10 4 3 2 0
Six months 11 3 3 2 0
  Proximal tibia (n = 18)
Before treatment 0 14 2 2 0
Three months 10 5 1 2 0
Six months 13 2 1 2 0
  Distal tibia (n = 7)
Before treatment 0 6 1 0 0
Three months 3 4 0 0 0
Six months 3 4 0 0 0
  Hindfoot (n = 21)
Before treatment 0 21 0 0 0
Three months 12 8 1 0 0
Six months 14 5 2 0 0
  Middlefoot (n = 7)
Before treatment 0 7 0 0 0
Three months 6 1 0 0 0
Six months 6 1 0 0 0
  Humerus (n = 3)
Before treatment 0 1 1 0 1
Three months 0 0 2 0 1
Six months 0 0 2 0 1