TY - JOUR AU - Braun, J. AU - Bollow, M. AU - Neure, L. AU - Seipelt, E. AU - Seyrekbasan, F. AU - Herbst, H. AU - Eggens, U. AU - Distler, A. AU - Sieper, J. PY - 1995 DA - 1995// TI - Use of immunohistologic and in situhybridization techniques in the examination of sacroiliac joint biopsy specimens from patients with ankylosing spondylitis JO - Arthritis Rheum VL - 38 UR - https://doi.org/10.1002/art.1780380407 DO - 10.1002/art.1780380407 ID - Braun1995 ER - TY - JOUR AU - Braun, J. AU - Brandt, J. AU - Listing, J. AU - Zink, A. AU - Alten, R. AU - Golder, W. AU - Gromnica-Ihle, E. AU - Kellner, H. AU - Krause, A. AU - Schneider, M. AU - Sörensen, H. AU - Zeidler, H. AU - Thriene, W. AU - Sieper, J. PY - 2002 DA - 2002// TI - Treatment of active ankylosing spondylitis with infliximab: a randomised controlled multicentre trial JO - Lancet VL - 359 UR - https://doi.org/10.1016/S0140-6736(02)08215-6 DO - 10.1016/S0140-6736(02)08215-6 ID - Braun2002 ER - TY - JOUR AU - Davis, J. C. AU - Heijde, D. V. a. n. D. e. r. AU - Braun, J. AU - Dougados, M. AU - Cush, J. AU - Clegg, D. O. AU - Kivitz, A. AU - Fleischmann, R. AU - Inman, R. AU - Tsuji, W. PY - 2003 DA - 2003// TI - Recombinant human tumor necrosis factor receptor (etanercept) for treating ankylosing spondylitis: a randomized, controlled trial JO - Arthritis Rheum VL - 48 UR - https://doi.org/10.1002/art.11325 DO - 10.1002/art.11325 ID - Davis2003 ER - TY - JOUR AU - Heijde, D. v. a. n. d. e. r. AU - Kivitz, A. AU - Schiff, M. H. AU - Sieper, J. AU - Dijkmans, B. A. AU - Braun, J. AU - Dougados, M. AU - Reveille, J. D. AU - Wong, R. L. AU - Kupper, H. AU - Davis, J. C. PY - 2006 DA - 2006// TI - Efficacy and safety of adalimumab in patients with ankylosing spondylitis: results of a multicenter, randomized, double-blind, placebo-controlled trial JO - Arthritis Rheum VL - 54 UR - https://doi.org/10.1002/art.21913 DO - 10.1002/art.21913 ID - Heijde2006 ER - TY - JOUR AU - Braun, J. AU - Landewe, R. AU - Hermann, K. G. AU - Han, J. AU - Yan, S. AU - Williamson, P. AU - Heijde, D. v. a. n. d. e. r. PY - 2006 DA - 2006// TI - Major reduction in spinal inflammation in patients with ankylosing spondylitis after treatment with infliximab: results of a multicenter, randomized, double-blind, placebo-controlled magnetic resonance imaging study JO - Arthritis Rheum VL - 54 UR - https://doi.org/10.1002/art.21790 DO - 10.1002/art.21790 ID - Braun2006 ER - TY - JOUR AU - Cruickshank, B. PY - 1971 DA - 1971// TI - Pathology of ankylosing spondylitis JO - Clin Orthop Relat Res VL - 74 ID - Cruickshank1971 ER - TY - JOUR AU - Bywaters, E. G. L. AU - Olsen, E. PY - 1968 DA - 1968// TI - Clinicopathological conference. A case of early ankylosing spondylitis with fatal secondary amyloidosis JO - Br Med J VL - 2 UR - https://doi.org/10.1136/bmj.2.5602.412 DO - 10.1136/bmj.2.5602.412 ID - Bywaters1968 ER - TY - JOUR AU - Appel, H. AU - Kuhne, M. AU - Spiekermann, S. AU - Kohler, D. AU - Zacher, J. AU - Stein, H. AU - Sieper, J. AU - Loddenkemper, C. PY - 2006 DA - 2006// TI - Immunohistochemical analysis of hip arthritis in ankylosing spondylitis: evaluation of the bone-cartilage interface and subchondral bone marrow JO - Arthritis Rheum VL - 54 UR - https://doi.org/10.1002/art.21907 DO - 10.1002/art.21907 ID - Appel2006 ER - TY - JOUR AU - Francois, R. J. AU - Gardner, D. L. AU - Degrave, E. J. AU - Bywaters, E. G. PY - 2000 DA - 2000// TI - Histopathologic evidence that sacroiliitis in ankylosing spondylitis is not merely enthesitis JO - Arthritis Rheum VL - 43 UR - https://doi.org/3.0.CO;2-Y DO - 3.0.CO;2-Y ID - Francois2000 ER - TY - JOUR AU - Savill, D. L. PY - 1951 DA - 1951// TI - The manubrio-sternal joint in ankylosing spondylitis JO - J Bone Joint Surg Br VL - 33 ID - Savill1951 ER - TY - JOUR AU - Appel, H. AU - Kuhne, M. AU - Spiekermann, S. AU - Ebhardt, H. AU - Groszdanovic, Z. AU - Köhler, D. AU - Dreimann, M. AU - Hempfing, A. AU - Rudwaleit, M. AU - Stein, H. AU - Metz-Stavenhagen, P. AU - Sieper, J. AU - Loddenkemper, C. PY - 2006 DA - 2006// TI - Immunohistological analysis of zygapophyseal joints in patients with ankylosing spondylitis JO - Arthritis Rheum VL - 54 UR - https://doi.org/10.1002/art.22060 DO - 10.1002/art.22060 ID - Appel2006 ER - TY - JOUR AU - Appel, H. AU - Loddenkemper, C. AU - Kuhne, M. AU - Spiekermann, S. AU - Ebhardt, H. AU - Grozdanovic, Z. AU - Köhler, D. AU - Dreimann, M. AU - Hempfing, A. AU - Metz-Stavenhagen, P. AU - Rudwaleit, M. AU - Sieper, J. PY - 2006 DA - 2006// TI - Correlation of histopathological findings and magnetic resonance imaging in the spine of patients with ankylosing spondylitis JO - Arthritis Res Ther VL - 8 UR - https://doi.org/10.1186/ar2035 DO - 10.1186/ar2035 ID - Appel2006 ER - TY - JOUR AU - Jain, R. K. PY - 2003 DA - 2003// TI - Molecular regulation of vessel maturation JO - Nat Med VL - 9 UR - https://doi.org/10.1038/nm0603-685 DO - 10.1038/nm0603-685 ID - Jain2003 ER - TY - JOUR AU - Drouart, M. AU - Saas, P. AU - Billot, M. AU - Cedoz, J. P. AU - Tiberghien, P. AU - Wendling, D. AU - Toussirot, E. PY - 2003 DA - 2003// TI - High serum vascular endothelial growth factor correlates with disease activity of spondylarthropathies JO - Clin Exp Immunol VL - 132 UR - https://doi.org/10.1046/j.1365-2249.2003.02101.x DO - 10.1046/j.1365-2249.2003.02101.x ID - Drouart2003 ER - TY - JOUR AU - Murphy, G. AU - Knäuper, V. AU - Atkinson, S. AU - Butler, G. AU - English, W. AU - Hutton, M. AU - Stracke, J. AU - Clark, I. PY - 2002 DA - 2002// TI - Matrix metalloproteinases in arthritic disease JO - Arthritis Res VL - 4 Suppl 3 UR - https://doi.org/10.1186/ar572 DO - 10.1186/ar572 ID - Murphy2002 ER - TY - JOUR AU - Zhu, J. AU - Yu, D. T. PY - 2006 DA - 2006// TI - Matrix metalloproteinase expression in the spondyloarthropathies JO - Curr Opin Rheumatol VL - 18 UR - https://doi.org/10.1097/01.bor.0000231904.04548.09 DO - 10.1097/01.bor.0000231904.04548.09 ID - Zhu2006 ER - TY - JOUR AU - Chen, C. H. AU - Lin, K. C. AU - Yu, D. T. AU - Yang, C. AU - Huang, F. AU - Chen, H. A. AU - Liang, T. H. AU - Liao, H. T. AU - Tsai, C. Y. AU - Wei, J. C. AU - Chou, C. T. PY - 2006 DA - 2006// TI - Serum matrix metalloproteinases and tissue inhibitors of metalloproteinases in ankylosing spondylitis: MMP-3 is a reproducibly sensitive and specific biomarker of disease activity JO - Rheumatology (Oxford) VL - 45 UR - https://doi.org/10.1093/rheumatology/kei208 DO - 10.1093/rheumatology/kei208 ID - Chen2006 ER - TY - JOUR AU - Maksymowych, W. P. AU - Poole, A. R. AU - Hiebert, L. AU - Webb, A. AU - Ionescu, M. AU - Lobanok, T. AU - King, L. AU - Davis, J. C. PY - 2005 DA - 2005// TI - Etanercept exerts beneficial effects on articular cartilage biomarkers of degradation and turnover in patients with ankylosing spondylitis JO - J Rheumatol VL - 32 ID - Maksymowych2005 ER - TY - JOUR AU - Maksymowych, W. P. AU - Landewé, R. AU - Conner-Spady, B. AU - Dougados, M. AU - Mielants, H. AU - Tempel, H. v. a. n. d. e. r. AU - Poole, A. R. AU - Wang, N. AU - Heijde, D. v. a. n. d. e. r. PY - 2007 DA - 2007// TI - Serum matrix metalloproteinase 3 is an independent predictor of structural damage progression in patients with ankylosing spondylitis JO - Arthritis Rheum VL - 56 UR - https://doi.org/10.1002/art.22589 DO - 10.1002/art.22589 ID - Maksymowych2007 ER - TY - JOUR AU - Weaver, C. M. AU - Peacock, M. AU - Martin, B. R. AU - McCabe, G. P. AU - Zhao, J. AU - Smith, D. L. AU - Wastney, M. E. PY - 1997 DA - 1997// TI - Quantification of biochemical markers of bone turnover by kinetic measures of bone formation and resorption in young healthy females JO - J Bone Miner Res VL - 12 UR - https://doi.org/10.1359/jbmr.1997.12.10.1714 DO - 10.1359/jbmr.1997.12.10.1714 ID - Weaver1997 ER - TY - JOUR AU - Rudwaleit, M. AU - Khan, M. A. AU - Sieper, J. PY - 2005 DA - 2005// TI - The challenge of diagnosis and classification in early ankylosing spondylitis: do we need new criteria? JO - Arthritis Rheum VL - 52 UR - https://doi.org/10.1002/art.20990 DO - 10.1002/art.20990 ID - Rudwaleit2005 ER - TY - JOUR AU - Haibel, H. AU - Rudwaleit, M. AU - Listing, J. AU - Heldmann, F. AU - Wong, R. L. AU - Kupper, H. AU - Braun, J. AU - Sieper, J. PY - 2008 DA - 2008// TI - Efficacy of adalimumab in the treatment of axial spondylarthritis without radiographically defined sacroiliitis: results of a twelve-week randomized, double-blind, placebo-controlled trial followed by an open-label extension up to week fifty-two JO - Arthritis Rheum VL - 58 UR - https://doi.org/10.1002/art.23606 DO - 10.1002/art.23606 ID - Haibel2008 ER - TY - JOUR AU - Haibel, H. AU - Rudwaleit, M. AU - Brandt, H. C. AU - Grozdanovic, Z. AU - Listing, J. AU - Kupper, H. AU - Braun, J. AU - Sieper, J. PY - 2006 DA - 2006// TI - Adalimumab reduces spinal symptoms in active ankylosing spondylitis: clinical and magnetic resonance imaging results of a fifty-two-week open-label trial JO - Arthritis Rheum VL - 54 UR - https://doi.org/10.1002/art.21563 DO - 10.1002/art.21563 ID - Haibel2006 ER - TY - JOUR AU - Visvanathan, S. AU - Wagner, C. L. AU - Marini, J. C. AU - Heijde, D. v. a. n. d. e. r. AU - Baker, D. AU - Gathany, T. AU - Han, J. AU - Braun, J. PY - 2008 DA - 2008// TI - Inflammatory biomarkers, disease activity, and spinal disease measures in patients with ankylosing spondylitis after treatment with infliximab JO - Ann Rheum Dis VL - 67 UR - https://doi.org/10.1136/ard.2007.071605 DO - 10.1136/ard.2007.071605 ID - Visvanathan2008 ER - TY - STD TI - Visvanathan S, Heijde van der D, Deodhar A, Wagner C, Baker DG, Han J, Braun J: Effects of infliximab on markers of inflammation and bone turnover and associations with bone mineral density in patients with ankylosing spondylitis. Ann Rheum Dis ID - ref25 ER - TY - JOUR AU - Woo, J. H. AU - Lee, H. J. AU - Sung, I. H. AU - Kim, T. H. PY - 2007 DA - 2007// TI - Changes of clinical response and bone biochemical markers in patients with ankylosing spondylitis taking etanercept JO - J Rheumatol VL - 34 ID - Woo2007 ER - TY - JOUR AU - Yang, C. AU - Gu, J. AU - Rihl, M. AU - Baeten, D. AU - Huang, F. AU - Zhao, M. AU - Zhang, H. AU - Maksymowych, W. P. AU - De Keyser, F. AU - Veys, E. M. AU - Yu, D. T. PY - 2004 DA - 2004// TI - Serum levels of matrix metalloproteinase 3 and macrophage colony-stimulating factor 1 correlate with disease activity in ankylosing spondylitis JO - Arthritis Rheum VL - 51 UR - https://doi.org/10.1002/art.20696 DO - 10.1002/art.20696 ID - Yang2004 ER - TY - JOUR AU - Mitra, D. AU - Elvins, D. M. AU - Collins, A. J. PY - 1999 DA - 1999// TI - Biochemical markers of bone metabolism in mild ankylosing spondylitis and their relationship with bone mineral density and vertebral fractures JO - J Rheumatol VL - 26 ID - Mitra1999 ER - TY - JOUR AU - Vandooren, B. AU - Kruithof, E. AU - Yu, D. T. AU - Rihl, M. AU - Gu, J. AU - De Rycke, L. AU - Bosch, F. V. a. n. D. e. n. AU - Veys, E. M. AU - De Keyser, F. AU - Baeten, D. PY - 2004 DA - 2004// TI - Involvement of matrix metalloproteinases and their inhibitors in peripheral synovitis and down-regulation by tumor necrosis factor alpha blockade in spondylarthropathy JO - Arthritis Rheum VL - 50 UR - https://doi.org/10.1002/art.20477 DO - 10.1002/art.20477 ID - Vandooren2004 ER - TY - JOUR AU - Sieper, J. AU - Appel, H. AU - Braun, J. AU - Rudwaleit, M. PY - 2008 DA - 2008// TI - Critical appraisal of assessment of structural damage in ankylosing spondylitis: implications for treatment outcomes JO - Arthritis Rheum VL - 58 UR - https://doi.org/10.1002/art.23260 DO - 10.1002/art.23260 ID - Sieper2008 ER - TY - JOUR AU - Briot, K. AU - Garnero, P. AU - Gossec, L. AU - Charni, N. AU - Kolta, S. AU - Dougados, M. AU - Roux, C. PY - 2006 DA - 2006// TI - Etanercept has beneficial effects on bone and cartilage metabolism in patients with ankylosing spondylitis [abstract] JO - Arthritis Rheum VL - 59 ID - Briot2006 ER - TY - JOUR AU - Allali, F. AU - Breban, M. AU - Porcher, R. AU - Maillefert, J. F. AU - Dougados, M. AU - Roux, C. PY - 2003 DA - 2003// TI - Increase in bone mineral density of patients with spondyloarthropathy treated with anti-tumour necrosis factor alpha JO - Ann Rheum Dis VL - 62 UR - https://doi.org/10.1136/ard.62.4.347 DO - 10.1136/ard.62.4.347 ID - Allali2003 ER - TY - JOUR AU - Linden, S. M. v. a. n. d. e. r. AU - Valkenburg, H. A. AU - de Jongh, B. M. AU - Cats, A. PY - 1984 DA - 1984// TI - The risk of developing ankylosing spondylitis in HLA-B27 positive individuals. A comparison of relatives of spondylitis patients with the general population JO - Arthritis Rheum VL - 27 UR - https://doi.org/10.1002/art.1780270301 DO - 10.1002/art.1780270301 ID - Linden1984 ER -