Association of a single nucleotide polymorphism in growth differentiate factor 5 with congenital dysplasia of the hip: a case-control study

Table 2 Genotype and allele frequencies of C/T transition SNP (rs143383) of the GDF5 gene in different CDH categories when stratified by severity

Group	Number of subjects (%)	Genotype (frequency)			Allele (frequency)		Hardy-Weinberg equilibrium
		TT	TC	CC	T	C	P value
CDH
Instability	21 (6%)	14 (0.667)	6 (0.286)	1 (0.047)	34 (0.810)	8 (0.190)	0.74
subluxation	53 (16%)	33 (0.622)	18 (0.340)	2 (0.038)	84(0.792)	22(0.208)	0.81
Dislocation	264 (78%)	167 (0.633)	87 (0.329)	10 (0.038)	421 (0.797)	107 (0.203)	0.75

CDH = congenital dysplasia of the hip; GDF5 = growth differentiate factor 5; SNP = single nucleotide polymorphism.

ISSN: 1478-6362