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Figure 10 | Arthritis Research & Therapy

Figure 10

From: Mapping similarities in mTOR pathway perturbations in mouse lupus nephritis models and human lupus nephritis

Figure 10

Complement pathway modulated by sirolimus treatment. Expression of components of the complement pathway in sirolimus-treated tissue compared with asymptomatic tissue. Green colour indicates increased expression and red colour indicates decreased expression. Grey colour indicates that the fold change and FDR p < 0.05 or the sigPathway FDR p < 0.05 filters were not met. The names of the genes are in "nodes". The shape of the nodes is related to gene function/family membership. The lines between the nodes represent the connectivity between genes. Solid lines indicate direct protein-protein interactions. Dotted lines represent indirect interactions.

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