Figure 8

Antigen presentation pathway modulated by sirolimus treatment. Expression of components of the antigen presentation pathway in sirolimus-treated tissue compared with asymptomatic tissue. Green colour indicates higher level of expression in sirolimus-treated tissue and red colour indicates lower level of expression in sirolimus-treated tissue. Grey colour indicates no significant difference in expression level. The names of the genes are in "nodes". The shape of the nodes is related to gene function/family membership. The lines between the nodes represent the connectivity between genes. Solid lines indicate direct protein-protein interactions. Dotted lines represent indirect interactions.