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Table 1 Baseline characteristics of the 150 patients treated with or without prednisolone

From: Impact of low-dose prednisolone on bone synthesis and resorption in early rheumatoid arthritis: experiences from a two-year randomized study

 

Prednisolone n = 70

No prednisolone n = 80

p level

Age, years

51.3(48.2 to 54.4)

58.4 (55.6 to 61.2)

0.001

Disease duration, months

6.3 (5.5 to 7.1)

5.7 (5.1 to 6.4)

0.27

Women, %

69

65

0.64

Menopause, %

50

69

0.05

Menopause age, years*

50(48 to 51)

50(47 to 52)

0.97

Current or previous smoker, %

67

56

0.13

BMI*, kg/m2

24.3 (22.5 to 27.0)

25.6 (23.5 to 29.1)

0.07

RF positivity, %

66

55

0.25

Erosive disease, %

53

56

0.68

DAS28

5.2 (4.9 to 5.5)

5.5 (5.3 to 5.7)

0.12

ESR

39(33 to 44)

39(33 to 45)

0.96

CRP*

22(10 to 45)

21(10 to 58)

0.50

IL-6*

9.9(8.0 to 19.4)

11.7(9.2 to 27.6)

0.44

HAQ

1.0 (0.9 to 1.2)

1.0 (0.8 to 1.1)

0.52

Z-score, L2–L4*

0.36 (-0.24 to 0.88)

0.50 (-0.36 to 1.37)

0.29

Z-score neck*

0.01 (-0.56 to 1.00)

-0.02 (-0.52 to 0.69)

0.87

P1NP*, μg/L

38.3 (28.0 to 51.8)

40.8 (28.8 to 57.0)

0.50

CTX-1*, ng/mL

0.26 (0.20 to 0.35)

0.33 (0.19 to 0.42)

0.17

1CTP* μg/L

4.5 (3.5 to 5.7)

4.2 (3.4 to 6.4)

0.62

IGF-1, μg/L*

173 (135 to 202)

210 (185 to 250)

0.34

IGFSD

0.15 (-0.06 to 0.6)

1.0 (0.4 to 1.6)

0.42

  1. Data presented as mean (95% confidence interval) or median (interquartile range).
  2. * depending on its distribution.
  3. BMI = body mass index; CRP = C-reactive protein; 1CTP = C-terminal propeptide of type I collagen; CTX-1 = C-terminal telopeptide of type I collagen; DAS = disease activity score; ESR = erythrocyte sedimentation rate; HAQ = health assessment questionnaire; IGF-1 = insulin-like growth factor 1; IGFSD = IGF-1, standard deviation-scores; IL-6 = interleukin-6; P1NP = Procollagen type I N-terminal propeptide; RF = rheumatoid factor. Bold p values are statistically significant.