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Table 2 Dual X-ray absorptiometry measurements at baseline and the changes after two years, separated for the two treatment groups

From: Impact of low-dose prednisolone on bone synthesis and resorption in early rheumatoid arthritis: experiences from a two-year randomized study

  P-group NoP-group P vs NoP
  Baseline Change baseline to 2 years p value change Baseline Change baseline to 2 years p value change p value change
BMD, g/cm2 L2 to L4 1.180 (1.070 to 1.263) -0.032 (-0.063 to 0.010) = -2.8 (-5.9 to 1.0) % <0.001 1.119 (1.063 to 1.227) -0.013 (-0.054 to 0.025) = -1.1(-4.8 to 2.0) % 0.034 0.08
Z-score L2 to L4 0.36 (-0.24 to 0.88) -0.30 (-0.60 to -0.01) <0.001 0.50 (-0.36 to 1.37) -0.10 (-0.51 to 0.24) 0.029 0.043
T-score L2 to L4 -0.17 (-1.03 to 0.56) -0.30 (-0.51 to 0.06) <0.001 -0.37 (-1.16 to 0.42) -0.10 (-0.45 to 0.20) 0.035 0.07
BMD, g/cm2 neck 0.963 (0.837 to 1.047) -0.008 (-0.045 to 0.021) = -0.75 (-4.9 to 2.2) % 0.20 0.903 (0.813 to 0.981) -0.014 (-0.056 to 0.006) = -1.9 (-6.5 to 0.6) % <0.001 0.16
Z-score neck 0.01 (-0.56 to 1.00) -0.05 (-0.32 to 0.21) 0.43 -0.02 (-0.52 to 0.69) -0.10 (-0.46 to 0.11) 0.007 0.27
T-score neck -0.50 (-1.66 to 0.30) -0.03 (-0.39 to 0.18) 0.24 -0.84 (-1.58- to 0.22) -0.13 (-0.46 to 0.05) <0.001 0.12
  1. Data is presented as median (interquartile range). Changes between baseline and two years are expressed as absolute difference for Z- scores and T-scores and for bone mineral density (BMD) also in percent. P = prednisolone-treated group, No-P = No prednisolone treated group. Bold p values are statistically significant.