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Table 2 Dual X-ray absorptiometry measurements at baseline and the changes after two years, separated for the two treatment groups

From: Impact of low-dose prednisolone on bone synthesis and resorption in early rheumatoid arthritis: experiences from a two-year randomized study

 

P-group

NoP-group

P vs NoP

 

Baseline

Change baseline to 2 years

p value change

Baseline

Change baseline to 2 years

p value change

p value change

BMD, g/cm2 L2 to L4

1.180 (1.070 to 1.263)

-0.032 (-0.063 to 0.010) = -2.8 (-5.9 to 1.0) %

<0.001

1.119 (1.063 to 1.227)

-0.013 (-0.054 to 0.025) = -1.1(-4.8 to 2.0) %

0.034

0.08

Z-score L2 to L4

0.36 (-0.24 to 0.88)

-0.30 (-0.60 to -0.01)

<0.001

0.50 (-0.36 to 1.37)

-0.10 (-0.51 to 0.24)

0.029

0.043

T-score L2 to L4

-0.17 (-1.03 to 0.56)

-0.30 (-0.51 to 0.06)

<0.001

-0.37 (-1.16 to 0.42)

-0.10 (-0.45 to 0.20)

0.035

0.07

BMD, g/cm2 neck

0.963 (0.837 to 1.047)

-0.008 (-0.045 to 0.021) = -0.75 (-4.9 to 2.2) %

0.20

0.903 (0.813 to 0.981)

-0.014 (-0.056 to 0.006) = -1.9 (-6.5 to 0.6) %

<0.001

0.16

Z-score neck

0.01 (-0.56 to 1.00)

-0.05 (-0.32 to 0.21)

0.43

-0.02 (-0.52 to 0.69)

-0.10 (-0.46 to 0.11)

0.007

0.27

T-score neck

-0.50 (-1.66 to 0.30)

-0.03 (-0.39 to 0.18)

0.24

-0.84 (-1.58- to 0.22)

-0.13 (-0.46 to 0.05)

<0.001

0.12

  1. Data is presented as median (interquartile range). Changes between baseline and two years are expressed as absolute difference for Z- scores and T-scores and for bone mineral density (BMD) also in percent. P = prednisolone-treated group, No-P = No prednisolone treated group. Bold p values are statistically significant.