Table 1 Average of absolute value of cartilage loss in the global, lateral and medial compartments at 6, 12, and 24 months of follow-up
Volume (mm3) | Mean thickness (mm) | |||||
|---|---|---|---|---|---|---|
Licofelone | Naproxen | p-value | Licofelone | Naproxen | p-value | |
Global | ||||||
6 mo | -309.7 ± 238.9 | -357.8 ± 320.3 | 0.140 | -0.043 ± 0.034 | -0.051 ± 0.047 | 0.093 |
12 mo | -438.7 ± 252.9 | -543.3 ± 287.3 | 0.0009 | -0.061 ± 0.034 | -0.078 ± 0.040 | <0.0001 |
24 mo | -701.6 ± 331.9 | -853.2 ± 299.0 | <0.0001 | -0.095 ± 0.040 | -0.119 ± 0.041 | <0.0001 |
Lateral | ||||||
6 mo | -130.8 ± 143.7 | -159.4 ± 143.4 | 0.085 | -0.038 ± 0.041 | -0.046 ± 0.043 | 0.091 |
12 mo | -192.1 ± 146.1 | -244.3 ± 168.2 | 0.004 | -0.056 ± 0.041 | -0.072 ± 0.049 | 0.002 |
24 mo | -290.7 ± 184.2 | -368.6 ± 161.4 | 0.0001 | -0.080 ± 0.051 | -0.105 ± 0.047 | <0.0001 |
Medial | ||||||
6 mo | -178.9 ± 157.2 | -198.3 ± 214.0 | 0.370 | -0.047 ± 0.043 | -0.056 ± 0.059 | 0.136 |
12 mo | -246.6 ± 185.3 | -299.0 ± 182.7 | 0.014 | -0.064 ± 0.050 | -0.084 ± 0.049 | 0.0006 |
24 mo | -410.9 ± 229.9 | -484.6 ± 237.1 | 0.007 | -0.107 ± 0.053 | -0.131 ± 0.061 | 0.0004 |