Table 3 Average of absolute value of cartilage loss (volume and mean thickness) in the medial central condyle and tibia at 6, 12 and 24 months of follow-up
Volume (mm3) | Mean thickness (mm) | |||||
|---|---|---|---|---|---|---|
Licofelone | Naproxen | p-value | Licofelone | Naproxen | p-value | |
Condyle | ||||||
6 mo | -34.0 ± 53.0 | -41.3 ± 62.4 | 0.271 | -0.040 ± 0.083 | -0.061 ± 0.102 | 0.056 |
12 mo | -48.5 ± 52.4 | -60.2 ± 52.0 | 0.053 | -0.062 ± 0.085 | -0.084 ± 0.082 | 0.020 |
24 mo | -91.9 ± 74.9 | -102.6 ± 73.9 | 0.215 | -0.130 ± 0.107 | -0.141 ± 0.109 | 0.370 |
Tibia | ||||||
6 mo | -41.8 ± 35.9 | -40.5 ± 34.5 | 0.755 | -0.099 ± 0.090 | -0.097 ± 0.090 | 0.815 |
12 mo | -55.8 ± 39.4 | -68.7 ± 44.3 | 0.008 | -0.134 ± 0.093 | -0.166 ± 0.116 | 0.010 |
24 mo | -77.4 ± 45.5 | -101.9 ± 55.3 | <0.0001 | -0.182 ± 0.100 | -0.239 ± 0.134 | <0.0001 |