Table 4 Average of absolute value of cartilage loss (volume and mean thickness) in the lateral central condyle and tibia at 6, 12 and 24 months of follow-up
Volume (mm3) | Mean thickness (mm) | |||||
|---|---|---|---|---|---|---|
Licofelone | Naproxen | p-value | Licofelone | Naproxen | p-value | |
Condyle | ||||||
6 mo | -21.5 ± 44.2 | -27.6 ± 40.7 | 0.210 | -0.031 ± 0.073 | -0.040 ± 0.078 | 0.299 |
12 mo | -25.5 ± 47.6 | -34.6 ± 44.7 | 0.088 | -0.039 ± 0.077 | -0.055 ± 0.081 | 0.078 |
24 mo | -35.1 ± 60.9 | -46.3 ± 40.0 | 0.062 | -0.047 ± 0.096 | -0.067 ± 0.072 | 0.040 |
Tibia | ||||||
6 mo | -33.3 ± 33.2 | -32.8 ± 39.3 | 0.899 | -0.091 ± 0.098 | -0.090 ± 0.110 | 0.940 |
12 mo | -44.7 ± 32.2 | -56.1 ± 32.9 | 0.003 | -0.124 ± 0.094 | -0.151 ± 0.095 | 0.013 |
24 mo | -71.9 ± 41.1 | -85.8 ± 41.9 | 0.004 | -0.203 ± 0.120 | -0.232 ± 0.110 | 0.032 |